Atomistry » Magnesium » PDB 4cgk-4cs3 » 4clu
Atomistry »
  Magnesium »
    PDB 4cgk-4cs3 »
      4clu »

Magnesium in PDB 4clu: Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate

Enzymatic activity of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate

All present enzymatic activity of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate:
4.6.1.1;

Protein crystallography data

The structure of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate, PDB code: 4clu was solved by S.Kleinboelting, M.Weyand, C.Steegborn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 87.21 / 1.90
Space group P 63
Cell size a, b, c (Å), α, β, γ (°) 100.700, 100.700, 97.150, 90.00, 90.00, 120.00
R / Rfree (%) 15.989 / 20.5

Other elements in 4clu:

The structure of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate (pdb code 4clu). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate, PDB code: 4clu:

Magnesium binding site 1 out of 1 in 4clu

Go back to Magnesium Binding Sites List in 4clu
Magnesium binding site 1 out of 1 in the Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Soluble Adenylyl Cyclase with Pyrophosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1475

b:56.2
occ:1.00
 OD1 A:ASP99 2.3 41.9 1.0
OD1 A:ASP47 2.6 38.0 1.0
O2 A:POP1470 2.8 63.7 1.0
O5 A:POP1470 2.9 77.4 1.0
O A:POP1470 3.1 77.1 1.0
O A:HOH2040 3.2 52.8 1.0
CG A:ASP99 3.4 42.0 1.0
P2 A:POP1470 3.4 84.5 1.0
CG A:ASP47 3.5 38.9 1.0
O4 A:POP1470 3.6 76.4 1.0
OD2 A:ASP47 3.6 42.8 1.0
P1 A:POP1470 3.7 75.4 1.0
OD2 A:ASP99 3.8 52.3 1.0
O A:HOH2071 4.2 36.6 1.0
O A:ILE48 4.3 47.1 1.0
O3 A:POP1470 4.5 67.0 1.0
N A:ASP99 4.6 30.7 1.0
OG1 A:THR52 4.7 38.8 1.0
CB A:ASP99 4.7 36.8 1.0
C A:ASP99 4.8 27.5 1.0
CB A:ALA100 4.8 23.4 1.0
O1 A:POP1470 4.9 76.2 1.0
CB A:ASP47 4.9 32.9 1.0
CA A:ASP99 4.9 33.4 1.0
N A:ALA100 4.9 28.1 1.0
O6 A:POP1470 4.9 74.6 1.0

Reference:

S.Kleinboelting, A.Diaz, S.Moniot, J.Van Den Heuvel, M.Weyand, L.R.Levin, J.Buck, C.Steegborn. Crystal Structures of Human Soluble Adenylyl Cyclase Reveal Mechanisms of Catalysis and of Its Activation Through Bicarbonate. Proc.Natl.Acad.Sci.Usa V. 111 3727 2014.
ISSN: ISSN 0027-8424
PubMed: 24567411
DOI: 10.1073/PNAS.1322778111
Page generated: Thu Aug 15 16:49:31 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy