Magnesium in PDB 4dv1: Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin

The structure of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin, PDB code: 4dv1 was solved by H.Demirci, F.Murphy Iv, E.Murphy, S.T.Gregory, A.E.Dahlberg, G.Jogl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.93 / 3.85
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	403.455, 403.455, 173.407, 90.00, 90.00, 90.00
R / Rfree (%)	15 / 21.2

The structure of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 70; Page 8, Binding sites: 71 - 80; Page 9, Binding sites: 81 - 90; Page 10, Binding sites: 91 - 100; Page 11, Binding sites: 101 - 110; Page 12, Binding sites: 111 - 120; Page 13, Binding sites: 121 - 130; Page 14, Binding sites: 131 - 140; Page 15, Binding sites: 141 - 150; Page 16, Binding sites: 151 - 160; Page 17, Binding sites: 161 - 170; Page 18, Binding sites: 171 - 180; Page 19, Binding sites: 181 - 190; Page 20, Binding sites: 191 - 200; Page 21, Binding sites: 201 - 210; Page 22, Binding sites: 211 - 220; Page 23, Binding sites: 221 - 230; Page 24, Binding sites: 231 - 240; Page 25, Binding sites: 241 - 247;

Binding sites:

The binding sites of Magnesium atom in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin (pdb code 4dv1). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 247 binding sites of Magnesium where determined in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin, PDB code: 4dv1:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1602 b:0.1 occ:1.00 O A:HOH1904 2.1 0.4 1.0 O A:HOH1903 2.1 0.4 1.0 O A:HOH1901 2.1 0.7 1.0 O A:HOH1902 2.1 78.1 1.0 O6 A:G377 2.9 0.5 1.0 C6 A:G377 4.0 0.8 1.0 N7 A:G377 4.0 1.0 1.0 O6 A:G376 4.0 0.4 1.0 N7 A:G376 4.1 0.1 1.0 C5 A:G377 4.4 0.8 1.0 C5 A:G376 4.4 0.5 1.0 C6 A:G376 4.4 0.7 1.0 C8 A:G376 4.9 0.2 1.0

Magnesium binding site 2 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1603 b:0.5 occ:1.00 O A:HOH1907 2.1 0.4 1.0 O A:HOH1905 2.1 0.9 1.0 O A:HOH1906 2.1 0.9 1.0 O6 A:G649 3.7 0.2 1.0 O6 A:G650 3.7 0.9 1.0 N7 A:G650 4.0 0.0 1.0 OP2 A:A753 4.3 0.5 1.0 C6 A:G649 4.4 0.9 1.0 C6 A:G650 4.5 0.8 1.0 N7 A:G649 4.5 0.7 1.0 C5 A:G650 4.6 0.2 1.0 C5 A:G649 4.8 1.0 1.0 OP1 A:A753 4.9 0.5 1.0 N4 A:C651 5.0 0.3 1.0

Magnesium binding site 3 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1604 b:0.6 occ:1.00 OP2 A:G654 2.7 0.2 1.0 P A:G654 4.0 0.3 1.0 N7 A:A655 4.0 0.4 1.0 O5' A:G654 4.3 0.4 1.0 OP2 A:A655 4.3 0.7 1.0 N6 A:A655 4.4 0.8 1.0 OP1 A:G654 4.8 0.3 1.0 C5 A:A655 4.9 0.4 1.0 C8 A:A655 4.9 0.6 1.0 N4 A:C656 5.0 0.1 1.0

Magnesium binding site 4 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1605 b:0.2 occ:1.00 O A:HOH1911 2.1 76.2 1.0 O A:HOH1909 2.1 0.3 1.0 O A:HOH1910 2.1 77.2 1.0 O A:HOH1908 2.1 88.0 1.0 OP2 A:G117 2.6 0.8 1.0 OP2 A:G289 3.0 0.2 1.0 P A:G117 3.5 0.5 1.0 OP1 A:G117 3.7 0.3 1.0 OP1 A:A116 3.8 0.3 1.0 O4 A:U118 3.8 0.0 1.0 OP2 A:A116 3.9 0.1 1.0 O5' A:A288 4.1 0.8 1.0 O3' A:A116 4.1 0.8 1.0 P A:G289 4.1 0.5 1.0 OP2 A:A288 4.2 0.2 1.0 C5 A:U118 4.3 0.9 1.0 P A:A116 4.3 0.5 1.0 C3' A:A288 4.3 0.5 1.0 C8 A:A288 4.3 0.2 1.0 OP1 A:G289 4.4 0.4 1.0 C4 A:U118 4.4 0.3 1.0 N7 A:G117 4.4 0.6 1.0 C3' A:A116 4.6 0.1 1.0 P A:A288 4.6 0.8 1.0 O3' A:A288 4.7 0.1 1.0 N7 A:A288 4.7 0.5 1.0 C8 A:G117 4.9 0.0 1.0 O5' A:G117 4.9 0.7 1.0

Magnesium binding site 5 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1606 b:0.4 occ:1.00 OP2 A:C48 2.7 0.5 1.0 OP1 A:G115 3.0 0.8 1.0 P A:C48 3.7 0.7 1.0 O5' A:C48 3.8 0.4 1.0 O3' A:U114 3.8 0.2 1.0 OP2 A:U49 3.8 0.2 1.0 OP1 A:A51 3.9 1.0 1.0 P A:G115 4.0 0.6 1.0 O3' A:C47 4.1 0.2 1.0 C5' A:A51 4.7 0.5 1.0 O2' A:C47 4.7 0.3 1.0 C5' A:G115 4.7 0.9 1.0 O5' A:A51 4.8 0.4 1.0 P A:A51 4.8 0.3 1.0 O5' A:G115 5.0 1.0 1.0

Magnesium binding site 6 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1607 b:0.9 occ:1.00 O A:HOH1915 2.1 0.8 1.0 O A:HOH1913 2.1 0.3 1.0 O A:HOH1914 2.1 0.7 1.0 O A:HOH1912 2.1 0.1 1.0 OP2 A:U652 4.1 0.3 1.0 N7 A:G752 4.3 0.7 1.0 OP1 A:C651 4.4 0.0 1.0 OP2 A:U751 4.5 0.7 1.0 C8 A:G752 4.9 0.5 1.0 O5' A:C651 4.9 0.1 1.0 P A:C651 5.0 0.1 1.0 OP2 A:G752 5.0 1.0 1.0

Magnesium binding site 7 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1608 b:0.7 occ:1.00 O A:HOH1918 2.1 0.3 1.0 O A:HOH1916 2.1 0.4 1.0 O A:HOH1917 2.1 87.0 1.0 O6 A:G800 3.6 0.6 1.0 O A:HOH2018 3.7 0.7 1.0 C6 A:G800 4.3 0.8 1.0 N7 A:G799 4.3 0.1 1.0 O6 A:G799 4.3 0.9 1.0 N7 A:G798 4.4 0.6 1.0 N1 A:G800 4.7 0.3 1.0 OP2 A:A780 4.8 0.1 1.0 NZ K:LYS122 4.9 0.5 1.0 O6 A:G798 5.0 0.5 1.0

Magnesium binding site 8 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1609 b:0.3 occ:1.00 O A:HOH1919 2.1 0.1 1.0 O A:HOH1920 2.1 93.3 1.0 OP1 A:G1508 2.5 0.8 1.0 OP1 A:A1500 2.6 0.5 1.0 OP1 A:G1505 2.7 0.6 1.0 O3' A:A1507 2.9 0.7 1.0 P A:G1508 3.2 0.8 1.0 C5' A:G1508 3.6 0.2 1.0 C3' A:G1504 3.8 0.8 1.0 P A:A1500 3.8 0.2 1.0 O5' A:G1508 3.9 0.2 1.0 OP2 A:C1501 4.0 0.7 1.0 P A:G1505 4.0 0.6 1.0 OP1 A:G1504 4.1 0.6 1.0 C3' A:A1507 4.2 0.6 1.0 O2' A:A1507 4.2 0.4 1.0 O5' A:G1504 4.2 0.2 1.0 C5' A:G1505 4.3 0.3 1.0 OP2 A:A1500 4.3 0.1 1.0 O5' A:G1505 4.4 0.5 1.0 O5' A:A1500 4.4 0.2 1.0 O3' A:G1504 4.4 0.1 1.0 OP2 A:G1508 4.5 0.4 1.0 C5' A:A1500 4.5 0.3 1.0 C2' A:G1504 4.5 0.3 1.0 P A:G1504 4.5 0.2 1.0 MG A:MG1708 4.5 0.9 1.0 C5' A:G1504 4.6 0.8 1.0 O2' A:U1506 4.7 0.2 1.0 C4' A:G1504 4.7 0.8 1.0 C2' A:A1507 4.8 0.2 1.0 C4' A:A1507 4.8 0.5 1.0 O2' A:G1504 4.8 0.8 1.0 OP2 A:G1504 4.8 0.8 1.0 C4' A:G1508 4.9 0.6 1.0

Magnesium binding site 9 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1610 b:0.5 occ:1.00 O A:HOH1921 2.1 84.1 1.0 O A:HOH1922 2.1 0.9 1.0 O6 A:G1526 3.5 0.4 1.0 N4 A:C1509 4.6 0.6 1.0 C6 A:G1526 4.7 0.8 1.0

Magnesium binding site 10 out of 247 in the Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of Crystal Structure of the Thermus Thermophilus 30S Ribosomal Subunit with A 16S Rrna Mutation, U20G, Bound with Streptomycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1611 b:0.3 occ:1.00 O A:HOH1925 2.1 0.5 1.0 O A:HOH1926 2.1 0.7 1.0 O A:HOH1923 2.1 0.9 1.0 O A:HOH1924 2.1 0.3 1.0 O A:HOH1927 2.1 89.2 1.0 OP2 A:G617 4.1 1.0 1.0 OP1 A:A621 4.2 0.1 1.0 OP1 A:C620 4.4 0.3 1.0 N7 A:G617 4.6 0.3 1.0 OP2 A:A621 4.7 0.7 1.0 P A:A621 4.9 0.2 1.0

H.Demirci, F.Murphy Iv, E.Murphy, S.T.Gregory, A.E.Dahlberg, G.Jogl. A Structural Basis For Streptomycin Resistance To Be Published.