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Atomistry » Magnesium » PDB 4nb4-4nln » 4neu » |
Magnesium in PDB 4neu: X-Ray Structure of Receptor Interacting Protein 1 (RIP1)Kinase Domain with A 1-Aminoisoquinoline InhibitorEnzymatic activity of X-Ray Structure of Receptor Interacting Protein 1 (RIP1)Kinase Domain with A 1-Aminoisoquinoline Inhibitor
All present enzymatic activity of X-Ray Structure of Receptor Interacting Protein 1 (RIP1)Kinase Domain with A 1-Aminoisoquinoline Inhibitor:
2.7.11.1; Protein crystallography data
The structure of X-Ray Structure of Receptor Interacting Protein 1 (RIP1)Kinase Domain with A 1-Aminoisoquinoline Inhibitor, PDB code: 4neu
was solved by
R.T.Nolte,
P.Ward,
K.M.Kahler,
N.Campobasso,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the X-Ray Structure of Receptor Interacting Protein 1 (RIP1)Kinase Domain with A 1-Aminoisoquinoline Inhibitor
(pdb code 4neu). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the X-Ray Structure of Receptor Interacting Protein 1 (RIP1)Kinase Domain with A 1-Aminoisoquinoline Inhibitor, PDB code: 4neu: Magnesium binding site 1 out of 1 in 4neuGo back to Magnesium Binding Sites List in 4neu
Magnesium binding site 1 out
of 1 in the X-Ray Structure of Receptor Interacting Protein 1 (RIP1)Kinase Domain with A 1-Aminoisoquinoline Inhibitor
Mono view Stereo pair view
Reference:
P.A.Harris,
D.Bandyopadhyay,
S.B.Berger,
N.Campobasso,
C.A.Capriotti,
J.A.Cox,
L.Dare,
J.N.Finger,
S.J.Hoffman,
K.M.Kahler,
R.Lehr,
J.D.Lich,
R.Nagilla,
R.T.Nolte,
M.T.Ouellette,
C.S.Pao,
M.C.Schaeffer,
A.Smallwood,
H.H.Sun,
B.A.Swift,
R.D.Totoritis,
P.Ward,
R.W.Marquis,
J.Bertin,
P.J.Gough.
Discovery of Small Molecule RIP1 Kinase Inhibitors For the Treatment of Pathologies Associated with Necroptosis. Acs Med Chem Lett V. 4 1238 2013.
Page generated: Mon Aug 19 23:32:26 2024
PubMed: 24900635 DOI: 10.1021/ML400382P |
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