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Atomistry » Magnesium » PDB 4pjj-4pyj » 4pl3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 4pjj-4pyj » 4pl3 » |
Magnesium in PDB 4pl3: Crystal Structure of Murine IRE1 in Complex with MKC9989 InhibitorEnzymatic activity of Crystal Structure of Murine IRE1 in Complex with MKC9989 Inhibitor
All present enzymatic activity of Crystal Structure of Murine IRE1 in Complex with MKC9989 Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Murine IRE1 in Complex with MKC9989 Inhibitor, PDB code: 4pl3
was solved by
M.Sanches,
N.Duffy,
M.Talukdar,
N.Thevakumaran,
D.Chiovitti,
R.Al-Awar,
J.B.Patterson,
F.Sicheri,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Murine IRE1 in Complex with MKC9989 Inhibitor
(pdb code 4pl3). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Murine IRE1 in Complex with MKC9989 Inhibitor, PDB code: 4pl3: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 4pl3Go back to Magnesium Binding Sites List in 4pl3
Magnesium binding site 1 out
of 2 in the Crystal Structure of Murine IRE1 in Complex with MKC9989 Inhibitor
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 4pl3Go back to Magnesium Binding Sites List in 4pl3
Magnesium binding site 2 out
of 2 in the Crystal Structure of Murine IRE1 in Complex with MKC9989 Inhibitor
Mono view Stereo pair view
Reference:
M.Sanches,
N.M.Duffy,
M.Talukdar,
N.Thevakumaran,
D.Chiovitti,
M.D.Canny,
K.Lee,
I.Kurinov,
D.Uehling,
R.Al-Awar,
G.Poda,
M.Prakesch,
B.Wilson,
V.Tam,
C.Schweitzer,
A.Toro,
J.L.Lucas,
D.Vuga,
L.Lehmann,
D.Durocher,
Q.Zeng,
J.B.Patterson,
F.Sicheri.
Structure and Mechanism of Action of the Hydroxy-Aryl-Aldehyde Class of IRE1 Endoribonuclease Inhibitors. Nat Commun V. 5 4202 2014.
Page generated: Tue Aug 20 01:34:19 2024
ISSN: ESSN 2041-1723 PubMed: 25164867 DOI: 10.1038/NCOMMS5202 |
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