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Atomistry » Magnesium » PDB 5iwa-5j2m » 5j1e | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 5iwa-5j2m » 5j1e » |
Magnesium in PDB 5j1e: Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse TranscriptaseEnzymatic activity of Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase
All present enzymatic activity of Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase:
2.7.7.49; 2.7.7.7; 3.1.26.4; Protein crystallography data
The structure of Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase, PDB code: 5j1e
was solved by
K.A.Kirby,
S.G.Sarafianos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase
(pdb code 5j1e). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase, PDB code: 5j1e: Jump to Magnesium binding site number: 1; 2; 3; Magnesium binding site 1 out of 3 in 5j1eGo back to Magnesium Binding Sites List in 5j1e
Magnesium binding site 1 out
of 3 in the Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase
Mono view Stereo pair view
Magnesium binding site 2 out of 3 in 5j1eGo back to Magnesium Binding Sites List in 5j1e
Magnesium binding site 2 out
of 3 in the Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase
Mono view Stereo pair view
Magnesium binding site 3 out of 3 in 5j1eGo back to Magnesium Binding Sites List in 5j1e
Magnesium binding site 3 out
of 3 in the Crystal Structure of A Hydroxypyridone Carboxylic Acid Active-Site Rnase H Inhibitor in Complex with Hiv Reverse Transcriptase
Mono view Stereo pair view
Reference:
J.Kankanala,
K.A.Kirby,
F.Liu,
L.Miller,
E.Nagy,
D.J.Wilson,
M.A.Parniak,
S.G.Sarafianos,
Z.Wang.
Design, Synthesis, and Biological Evaluations of Hydroxypyridonecarboxylic Acids As Inhibitors of Hiv Reverse Transcriptase Associated Rnase H. J.Med.Chem. V. 59 5051 2016.
Page generated: Sun Sep 29 17:10:48 2024
ISSN: ISSN 0022-2623 PubMed: 27094954 DOI: 10.1021/ACS.JMEDCHEM.6B00465 |
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