Magnesium in PDB 5syg: Cryo-Em Reconstruction of Zampanolide-Bound Microtubule

The binding sites of Magnesium atom in the Cryo-Em Reconstruction of Zampanolide-Bound Microtubule (pdb code 5syg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Reconstruction of Zampanolide-Bound Microtubule, PDB code: 5syg:

Magnesium binding site 1 out of 1 in the Cryo-Em Reconstruction of Zampanolide-Bound Microtubule


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Reconstruction of Zampanolide-Bound Microtubule within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:13.9 occ:1.00 O1B A:GTP501 2.2 0.1 1.0 OE1 A:GLU71 2.3 0.3 1.0 CB A:GLN11 2.9 77.9 1.0 OE1 A:GLN11 3.3 82.0 1.0 O1G A:GTP501 3.4 0.2 1.0 PB A:GTP501 3.4 0.8 1.0 CD A:GLU71 3.4 0.3 1.0 O3A A:GTP501 3.7 0.1 1.0 CG A:GLN11 3.8 81.4 1.0 N A:GLN11 3.8 77.8 1.0 CD A:GLN11 3.8 83.9 1.0 CA A:GLN11 3.8 80.0 1.0 OE2 A:GLU71 4.1 0.4 1.0 O1A A:GTP501 4.2 0.2 1.0 O3B A:GTP501 4.3 0.7 1.0 O B:ASN249 4.3 0.8 1.0 CG2 A:VAL74 4.4 84.4 1.0 PG A:GTP501 4.4 0.2 1.0 NZ B:LYS254 4.4 96.1 1.0 PA A:GTP501 4.5 0.7 1.0 CB A:GLU71 4.5 92.9 1.0 O2B A:GTP501 4.5 0.7 1.0 CG A:GLU71 4.5 98.0 1.0 OD2 A:ASP98 4.6 99.0 1.0 O2A A:GTP501 4.8 0.2 1.0 OD1 A:ASP69 4.9 81.5 1.0 NE2 A:GLN11 5.0 87.6 1.0

E.H.Kellogg, N.M.Hejab, S.Howes, P.Northcote, J.H.Miller, J.F.Diaz, K.H.Downing, E.Nogales. Insights Into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers From Cryo-Em Structures. J. Mol. Biol. V. 429 633 2017.
ISSN: ESSN 1089-8638
PubMed: 28104363
DOI: 10.1016/J.JMB.2017.01.001