|
Atomistry » Magnesium » PDB 5ske-5t19 » 5t19 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 5ske-5t19 » 5t19 » |
Magnesium in PDB 5t19: Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)AcetamideEnzymatic activity of Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)Acetamide
All present enzymatic activity of Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)Acetamide:
3.1.3.48; Protein crystallography data
The structure of Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)Acetamide, PDB code: 5t19
was solved by
A.R.Laciak,
J.J.Tanner,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5t19:
The structure of Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)Acetamide also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)Acetamide
(pdb code 5t19). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)Acetamide, PDB code: 5t19: Magnesium binding site 1 out of 1 in 5t19Go back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Structure of PTP1B Complexed with N-(3'-(1,1-Dioxido-4-Oxo-1,2,5- Thiadiazolidin-2-Yl)-4'-Methyl-[1,1'-Biphenyl]-4-Yl)Acetamide
![]() Mono view ![]() Stereo pair view
Reference:
P.Punthasee,
A.R.Laciak,
A.H.Cummings,
K.V.Ruddraraju,
S.M.Lewis,
R.Hillebrand,
H.Singh,
J.J.Tanner,
K.S.Gates.
Covalent Allosteric Inactivation of Protein Tyrosine Phosphatase 1B (PTP1B) By An Inhibitor-Electrophile Conjugate. Biochemistry V. 56 2051 2017.
Page generated: Mon Sep 30 04:42:36 2024
ISSN: ISSN 1520-4995 PubMed: 28345882 DOI: 10.1021/ACS.BIOCHEM.7B00151 |
Last articlesZn in 9J0NZn in 9J0O Zn in 9J0P Zn in 9FJX Zn in 9EKB Zn in 9C0F Zn in 9CAH Zn in 9CH0 Zn in 9CH3 Zn in 9CH1 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |