Magnesium in PDB 6hzm: Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (Alternative Placement of Magnesium Into the Cryo-Em Density)

The binding sites of Magnesium atom in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (Alternative Placement of Magnesium Into the Cryo-Em Density) (pdb code 6hzm). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (Alternative Placement of Magnesium Into the Cryo-Em Density), PDB code: 6hzm:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (Alternative Placement of Magnesium Into the Cryo-Em Density)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (Alternative Placement of Magnesium Into the Cryo-Em Density) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1502 b:16.1 occ:1.00 OG A:SER87 2.1 16.2 1.0 O1G A:ATP1501 2.3 17.9 1.0 O1B A:ATP1501 2.4 17.9 1.0 O A:HOH1602 2.5 15.9 1.0 OE1 A:GLN126 2.6 19.5 1.0 CD A:GLN126 3.1 19.5 1.0 O A:HOH1601 3.1 14.6 1.0 CB A:SER87 3.2 16.2 1.0 NE2 A:GLN126 3.4 19.5 1.0 PG A:ATP1501 3.5 17.9 1.0 OE1 A:GLN211 3.6 16.8 1.0 PB A:ATP1501 3.7 17.9 1.0 O3G A:ATP1501 3.9 17.9 1.0 OD1 A:ASP210 3.9 17.0 1.0 O3B A:ATP1501 4.0 17.9 1.0 CA A:SER87 4.3 16.2 1.0 N A:SER87 4.3 16.2 1.0 CG A:GLN126 4.3 19.5 1.0 CD A:GLN211 4.3 16.8 1.0 O1A A:ATP1501 4.5 17.9 1.0 O3A A:ATP1501 4.6 17.9 1.0 NE2 A:GLN211 4.6 16.8 1.0 CG A:ASP210 4.7 17.0 1.0 CB A:GLN126 4.8 19.5 1.0 O2G A:ATP1501 4.8 17.9 1.0 OD2 A:ASP210 4.8 17.0 1.0 N B:GLY188 4.8 17.1 1.0 O2B A:ATP1501 4.9 17.9 1.0 PA A:ATP1501 4.9 17.9 1.0

Magnesium binding site 2 out of 2 in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (Alternative Placement of Magnesium Into the Cryo-Em Density)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (Alternative Placement of Magnesium Into the Cryo-Em Density) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1502 b:16.1 occ:1.00 OG B:SER87 2.2 16.7 1.0 O1G B:ATP1501 2.3 18.4 1.0 O B:HOH1602 2.4 16.2 1.0 O1B B:ATP1501 2.5 18.4 1.0 OE1 B:GLN126 2.6 19.3 1.0 CD B:GLN126 3.1 19.3 1.0 CB B:SER87 3.2 16.7 1.0 O B:HOH1601 3.2 14.8 1.0 NE2 B:GLN126 3.3 19.3 1.0 PG B:ATP1501 3.5 18.4 1.0 OE1 B:GLN211 3.6 16.6 1.0 PB B:ATP1501 3.7 18.4 1.0 O3G B:ATP1501 3.9 18.4 1.0 O3B B:ATP1501 4.0 18.4 1.0 OD1 B:ASP210 4.0 16.9 1.0 CA B:SER87 4.3 16.7 1.0 CG B:GLN126 4.3 19.3 1.0 N B:SER87 4.3 16.7 1.0 CD B:GLN211 4.4 16.6 1.0 O1A B:ATP1501 4.5 18.4 1.0 O3A B:ATP1501 4.6 18.4 1.0 NE2 B:GLN211 4.7 16.6 1.0 CG B:ASP210 4.7 16.9 1.0 O2G B:ATP1501 4.8 18.4 1.0 CB B:GLN126 4.8 19.3 1.0 N A:GLY188 4.8 17.0 1.0 OD2 B:ASP210 4.9 16.9 1.0 PA B:ATP1501 4.9 18.4 1.0 O2B B:ATP1501 4.9 18.4 1.0

I.Manolaridis, S.M.Jackson, N.M.I.Taylor, J.Kowal, H.Stahlberg, K.P.Locher. Cryo-Em Structures of A Human ABCG2 Mutant Trapped in Atp-Bound and Substrate-Bound States. Nature V. 563 426 2018.
ISSN: ESSN 1476-4687
PubMed: 30405239
DOI: 10.1038/S41586-018-0680-3