Magnesium in PDB 6v2w: Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp

All present enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp:
2.7.11.1; 2.7.12.2;

The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp, PDB code: 6v2w was solved by K.Li, G.Gonzalez Del-Pino, E.Park, M.J.Eck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.30 / 3.12
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	116.278, 116.278, 129.739, 90.00, 90.00, 120.00
R / Rfree (%)	18.7 / 23.7

The binding sites of Magnesium atom in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp (pdb code 6v2w). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp, PDB code: 6v2w:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg802 b:71.2 occ:1.00 OD2 A:ASP594 2.2 62.0 1.0 O1B A:ANP801 2.2 66.4 1.0 OD1 A:ASN581 2.3 77.8 1.0 O1A A:ANP801 2.5 58.9 1.0 O2G A:ANP801 2.9 58.0 1.0 CG A:ASP594 3.4 73.2 1.0 CG A:ASN581 3.5 67.6 1.0 C8 A:ANP801 3.6 62.0 1.0 O A:ASN580 3.6 71.9 1.0 PA A:ANP801 3.6 77.8 1.0 PB A:ANP801 3.7 75.9 1.0 O5' A:ANP801 3.9 58.5 1.0 N7 A:ANP801 3.9 65.6 1.0 CA A:ASN581 4.0 62.4 1.0 O3A A:ANP801 4.1 80.2 1.0 CB A:ASN581 4.2 49.8 1.0 C A:ASN580 4.2 64.0 1.0 PG A:ANP801 4.3 71.7 1.0 OD1 A:ASP594 4.3 76.2 1.0 CB A:ASP594 4.3 71.0 1.0 N A:ASN581 4.4 66.2 1.0 ND2 A:ASN581 4.5 66.4 1.0 CZ A:PHE583 4.5 88.2 1.0 N3B A:ANP801 4.5 77.2 1.0 CE2 A:PHE583 4.6 86.5 1.0 C2' A:ANP801 4.6 69.1 1.0 N9 A:ANP801 4.6 59.6 1.0 O2B A:ANP801 4.6 65.5 1.0 NZ A:LYS483 4.9 78.1 1.0 O2A A:ANP801 5.0 84.7 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg802 b:74.2 occ:1.00 OD1 B:ASN195 2.0 86.3 1.0 O2A B:ANP801 2.0 82.1 1.0 O1B B:ANP801 2.4 89.7 1.0 CG B:ASN195 3.0 69.5 1.0 O1G B:ANP801 3.2 79.8 1.0 OD2 B:ASP208 3.2 84.1 1.0 ND2 B:ASN195 3.4 48.6 1.0 PA B:ANP801 3.5 87.4 1.0 NZ B:LYS97 3.5 0.6 1.0 CB B:ASP208 3.6 84.1 1.0 CG B:ASP208 3.7 84.1 1.0 PB B:ANP801 3.7 82.8 1.0 O3A B:ANP801 4.0 92.5 1.0 O1A B:ANP801 4.2 93.6 1.0 CB B:ASN195 4.3 66.8 1.0 PG B:ANP801 4.4 95.7 1.0 O B:SER194 4.4 73.2 1.0 O5' B:ANP801 4.6 78.1 1.0 N3B B:ANP801 4.6 74.9 1.0 CA B:ASN195 4.7 68.4 1.0 OD1 B:ASP208 4.8 84.1 1.0 O2B B:ANP801 4.8 75.8 1.0 C B:SER194 4.9 62.9 1.0 OD2 B:ASP190 4.9 0.9 1.0 N B:ASN195 5.0 66.6 1.0 CE B:LYS192 5.0 50.5 1.0 CE B:LYS97 5.0 91.0 1.0

K.Li, G.Gonzalez Del-Pino, E.Park, M.J.Eck. Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp To Be Published.