Magnesium in PDB 8ox5: Cryo-Em Structure of ATP8B1-CDC50A in E1P-Adp Conformation

All present enzymatic activity of Cryo-Em Structure of ATP8B1-CDC50A in E1P-Adp Conformation:
7.6.2.1;

The structure of Cryo-Em Structure of ATP8B1-CDC50A in E1P-Adp Conformation also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Aluminium	(Al)	1 atom

The binding sites of Magnesium atom in the Cryo-Em Structure of ATP8B1-CDC50A in E1P-Adp Conformation (pdb code 8ox5). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of ATP8B1-CDC50A in E1P-Adp Conformation, PDB code: 8ox5:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of ATP8B1-CDC50A in E1P-Adp Conformation


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of ATP8B1-CDC50A in E1P-Adp Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1203 b:34.1 occ:1.00 OD2 A:ASP454 1.5 33.1 1.0 F1 A:ALF1202 1.9 43.9 1.0 F4 A:ALF1202 2.1 43.9 1.0 CG A:ASP454 2.1 33.1 1.0 OD1 A:ASP893 2.2 28.5 1.0 O A:THR456 2.2 36.7 1.0 OE2 A:GLU914 2.5 35.5 1.0 AL A:ALF1202 2.8 43.9 1.0 OD1 A:ASP454 2.9 33.1 1.0 CG A:ASP893 3.0 28.5 1.0 CB A:ASP893 3.0 28.5 1.0 CB A:ASP454 3.0 33.1 1.0 C A:THR456 3.3 36.7 1.0 O1B A:ADP1201 3.4 54.1 1.0 CD A:GLU914 3.6 35.5 1.0 N A:THR456 3.8 36.7 1.0 CB A:THR456 3.8 36.7 1.0 CA A:THR456 3.8 36.7 1.0 O A:ASP893 4.1 28.5 1.0 OE1 A:GLU914 4.1 35.5 1.0 F3 A:ALF1202 4.2 43.9 1.0 OD2 A:ASP893 4.2 28.5 1.0 CA A:ASP893 4.2 28.5 1.0 C A:ASP893 4.2 28.5 1.0 F2 A:ALF1202 4.3 43.9 1.0 CA A:ASP454 4.3 33.1 1.0 O2B A:ADP1201 4.3 54.1 1.0 C A:ASP454 4.3 33.1 1.0 PB A:ADP1201 4.3 54.1 1.0 OD2 A:ASP897 4.4 30.3 1.0 O A:ASP454 4.4 33.1 1.0 N A:GLY457 4.5 29.7 1.0 CG2 A:THR456 4.6 36.7 1.0 OD1 A:ASN896 4.7 36.3 1.0 O3B A:ADP1201 4.7 54.1 1.0 ND2 A:ASN896 4.7 36.3 1.0 OG1 A:THR456 4.9 36.7 1.0 CG A:GLU914 4.9 35.5 1.0 N A:LYS455 4.9 37.2 1.0 N A:ASP893 4.9 28.5 1.0 CA A:GLY457 4.9 29.7 1.0 CG2 A:THR458 4.9 28.0 1.0

T.Dieudonne, F.Kummerer, M.J.Laursen, C.Stock, R.K.Flygaard, S.Khalid, G.Lenoir, J.A.Lyons, K.Lindorff-Larsen, P.Nissen. Activation and Substrate Specificity of the Human P4-Atpase ATP8B1. Nat Commun V. 14 7492 2023.
ISSN: ESSN 2041-1723
PubMed: 37980352
DOI: 10.1038/S41467-023-42828-9