Magnesium in PDB 1te6: Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom

All present enzymatic activity of Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom:
4.2.1.11;

The structure of Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom, PDB code: 1te6 was solved by G.Chai, J.Brewer, L.Lovelace, T.Aoki, W.Minor, L.Lebioda, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.80
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	114.579, 119.708, 68.216, 90.00, 90.00, 90.00
R / Rfree (%)	20.6 / 23.4

The structure of Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Magnesium atom in the Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom (pdb code 1te6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom, PDB code: 1te6:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in the Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg640 b:21.8 occ:1.00 OE2 A:GLU292 2.0 18.4 1.0 O A:HOH746 2.1 19.6 1.0 OD2 A:ASP317 2.1 19.4 1.0 OD2 A:ASP244 2.1 21.9 1.0 O A:HOH744 2.1 20.3 1.0 O A:HOH745 2.2 20.1 1.0 CG A:ASP244 3.0 20.7 1.0 CG A:ASP317 3.2 14.7 1.0 CD A:GLU292 3.2 22.7 1.0 OD1 A:ASP244 3.3 21.0 1.0 CB A:ASP317 3.7 17.4 1.0 NZ A:LYS393 3.8 21.4 1.0 O A:HOH747 3.8 17.9 1.0 NZ A:LYS342 3.9 19.5 1.0 OE1 A:GLN165 3.9 25.2 1.0 MG A:MG641 3.9 17.2 1.0 OE1 A:GLU292 3.9 20.1 1.0 O A:HOH748 3.9 18.1 1.0 CG A:GLU292 4.1 17.2 1.0 OD1 A:ASP317 4.2 18.6 1.0 OD2 A:ASP293 4.2 21.2 1.0 CD2 A:LEU340 4.2 20.3 1.0 CB A:ASP244 4.4 21.6 1.0 O1 A:PO4642 4.6 34.2 1.0 OE2 A:GLU166 4.8 24.3 1.0 CE A:LYS342 4.8 22.1 1.0 CE A:LYS393 4.8 19.1 1.0 O2 A:PO4642 4.9 21.4 1.0 CB A:ALA246 4.9 20.2 1.0 CG A:ASP293 4.9 22.3 1.0 CD A:GLN165 5.0 23.3 1.0

Magnesium binding site 2 out of 3 in the Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg641 b:17.2 occ:1.00 OG A:SER39 2.0 17.0 1.0 O A:SER39 2.0 17.5 1.0 O A:HOH748 2.1 18.1 1.0 O A:HOH747 2.1 17.9 1.0 O2 A:PO4642 2.1 21.4 1.0 O A:HOH744 2.1 20.3 1.0 CB A:SER39 3.0 18.1 1.0 C A:SER39 3.0 18.8 1.0 P A:PO4642 3.2 32.5 1.0 O1 A:PO4642 3.4 34.2 1.0 CA A:SER39 3.5 17.8 1.0 O3 A:PO4642 3.7 22.7 1.0 OD2 A:ASP317 3.8 19.4 1.0 MG A:MG640 3.9 21.8 1.0 NZ A:LYS342 3.9 19.5 1.0 N A:SER39 4.0 18.3 1.0 NE2 A:GLN165 4.1 17.8 1.0 O A:HOH746 4.1 19.6 1.0 OD2 A:ASP318 4.1 22.2 1.0 OE1 A:GLN165 4.2 25.2 1.0 N A:THR40 4.2 19.5 1.0 OD1 A:ASP318 4.3 20.3 1.0 NH2 A:ARG371 4.3 15.6 1.0 O A:HOH745 4.3 20.1 1.0 O4 A:PO4642 4.4 20.5 1.0 CD A:GLN165 4.6 23.3 1.0 CG A:ASP318 4.6 21.0 1.0 CA A:THR40 4.7 19.0 1.0 CG A:ASP317 4.9 14.7 1.0

Magnesium binding site 3 out of 3 in the Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of Human Neuron Specific Enolase at 1.8 Angstrom within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg740 b:21.6 occ:1.00 OD2 B:ASP317 2.0 19.9 1.0 O B:HOH751 2.0 16.8 1.0 OD2 B:ASP244 2.1 28.3 1.0 O B:HOH750 2.1 31.6 1.0 O B:HOH749 2.1 33.1 1.0 OE2 B:GLU292 2.1 20.1 1.0 CG B:ASP244 2.9 26.4 1.0 CG B:ASP317 3.1 24.6 1.0 OD1 B:ASP244 3.1 18.3 1.0 CD B:GLU292 3.3 25.6 1.0 CB B:ASP317 3.6 21.6 1.0 O B:HOH935 3.8 36.6 1.0 NZ B:LYS393 3.9 20.7 1.0 OD1 B:ASP317 4.1 24.1 1.0 CG B:GLU292 4.1 21.7 1.0 OE1 B:GLU292 4.1 22.6 1.0 NE2 B:GLN165 4.1 24.0 1.0 OD2 B:ASP293 4.2 25.1 1.0 OE2 B:GLU166 4.3 26.1 1.0 CB B:ASP244 4.4 21.3 1.0 CD2 B:LEU340 4.4 18.1 1.0 NZ B:LYS342 4.5 24.8 1.0 O B:HOH926 4.5 45.1 1.0 CG B:ASP293 5.0 24.6 1.0

G.Chai, J.Brewer, L.Lovelace, T.Aoki, W.Minor, L.Lebioda. Expression, Purification and the 1.8 A Resolution Crystal Structure of Human Neuron Specific Enolase J.Mol.Biol. V. 341 1015 2004.
ISSN: ISSN 0022-2836
PubMed: 15289101
DOI: 10.1016/J.JMB.2004.05.068