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Magnesium in PDB 2cm8: Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics
Enzymatic activity of Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics
All present enzymatic activity of Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics:
3.1.3.48;
3.1.3.48;
Protein crystallography data
The structure of Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics, PDB code: 2cm8
was solved by
P.J.Ala,
L.Gonneville,
M.C.Hillman,
M.Becker-Pasha,
M.Wei,
B.G.Reid,
R.Klabe,
E.W.Yue,
B.Wayland,
B.Douty,
A.P.Combs,
P.Polam,
Z.Wasserman,
M.Bower,
T.C.Burn,
G.F.Hollis,
R.Wynn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 8.00 / 2.10 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 88.290, 88.290, 104.170, 90.00, 90.00, 120.00 |
| R / Rfree (%) | n/a / n/a |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics
(pdb code 2cm8). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics, PDB code: 2cm8:
In total only one binding site of Magnesium was determined in the Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics, PDB code: 2cm8:
Magnesium binding site 1 out of 1 in 2cm8
Go back to
Magnesium Binding Sites List in 2cm8
Magnesium binding site 1 out
of 1 in the Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Structural Basis For Inhibition of Protein Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics within 5.0Å range:
|
Reference:
P.J.Ala,
L.Gonneville,
M.C.Hillman,
M.Becker-Pasha,
M.Wei,
B.G.Reid,
R.Klabe,
E.W.Yue,
B.Wayland,
B.Douty,
P.Polam,
Z.Wasserman,
M.Bower,
A.P.Combs,
T.C.Burn,
G.F.Hollis,
R.Wynn.
Structural Basis For Inhibition of Protein-Tyrosine Phosphatase 1B By Isothiazolidinone Heterocyclic Phosphonate Mimetics. J.Biol.Chem. V. 281 32784 2006.
ISSN: ISSN 0021-9258
PubMed: 16916797
DOI: 10.1074/JBC.M606873200
Page generated: Sun Aug 10 10:19:29 2025
ISSN: ISSN 0021-9258
PubMed: 16916797
DOI: 10.1074/JBC.M606873200
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