Atomistry » Magnesium » PDB 2ybb-2yni » 2yi7
Atomistry »
  Magnesium »
    PDB 2ybb-2yni »
      2yi7 »

Magnesium in PDB 2yi7: Structural Characterization of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole HSP90 Inhibitors.

Protein crystallography data

The structure of Structural Characterization of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole HSP90 Inhibitors., PDB code: 2yi7 was solved by S.M.Roe, C.Prodromou, L.H.Pearl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.35 / 1.40
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 65.230, 88.705, 99.625, 90.00, 90.00, 90.00
R / Rfree (%) 17.478 / 19.635

Other elements in 2yi7:

The structure of Structural Characterization of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole HSP90 Inhibitors. also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Structural Characterization of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole HSP90 Inhibitors. (pdb code 2yi7). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structural Characterization of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole HSP90 Inhibitors., PDB code: 2yi7:

Magnesium binding site 1 out of 1 in 2yi7

Go back to Magnesium Binding Sites List in 2yi7
Magnesium binding site 1 out of 1 in the Structural Characterization of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole HSP90 Inhibitors.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structural Characterization of 5-Aryl-4-(5-Substituted-2-4- Dihydroxyphenyl)-1,2,3-Thiadiazole HSP90 Inhibitors. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1226

b:16.5
occ:0.50
O A:HOH2117 1.9 28.1 1.0
O A:HOH3001 1.9 25.5 1.0
O A:HOH2118 2.2 21.8 1.0
O A:HOH2116 3.5 38.0 1.0
OD1 A:ASP54 4.2 17.1 1.0
OD2 A:ASP54 4.4 17.0 1.0
O A:HOH2051 4.5 25.3 1.0
O A:HOH2105 4.5 20.1 1.0
O A:HOH2052 4.7 31.7 0.5
CG A:ASP54 4.7 13.7 1.0

Reference:

S.Y.Sharp, S.M.Roe, E.Kazlauskas, I.Cikotiene, P.Workman, D.Matulis, C.Prodromou. Co-Crystalization and in Vitro Biological Characterization of 5-Aryl-4-(5-Substituted-2-4-Dihydroxyphenyl)-1,2,3- Thiadiazole HSP90 Inhibitors. Plos One V. 7E44642 2012.
ISSN: ISSN 1932-6203
PubMed: 22984537
DOI: 10.1371/JOURNAL.PONE.0044642
Page generated: Wed Aug 14 07:32:08 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy