Magnesium »
PDB 3kk2-3ktq »
3kkt »
Magnesium in PDB 3kkt: Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509.
Enzymatic activity of Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509.
All present enzymatic activity of Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509.:
3.1.4.17;
3.1.4.17;
Protein crystallography data
The structure of Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509., PDB code: 3kkt
was solved by
R.K.Y.Cheng,
L.Crawley,
J.Barker,
M.Whittaker,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 70.59 / 2.48 |
| Space group | P 65 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 89.740, 89.740, 337.443, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 23.5 / 29.5 |
Other elements in 3kkt:
The structure of Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509. also contains other interesting chemical elements:
| Zinc | (Zn) | 2 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509.
(pdb code 3kkt). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509., PDB code: 3kkt:
Jump to Magnesium binding site number: 1; 2;
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509., PDB code: 3kkt:
Jump to Magnesium binding site number: 1; 2;
Magnesium binding site 1 out of 2 in 3kkt
Go back to
Magnesium Binding Sites List in 3kkt
Magnesium binding site 1 out
of 2 in the Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509. within 5.0Å range:
|
Magnesium binding site 2 out of 2 in 3kkt
Go back to
Magnesium Binding Sites List in 3kkt
Magnesium binding site 2 out
of 2 in the Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)- Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)- Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502- 509. within 5.0Å range:
|
Reference:
R.K.Y.Cheng,
L.Crawley,
J.Barker,
M.Whittaker.
Crystal Structure of Human PDE4B with 5-[3-[(1S,2S,4R)-Bicyclo[2.2.1]Hept-2-Yloxy]-4-Methoxyp Henyl]Tetrahydro-2(1H)-Pyrimidinone Reveals Ordering of the C-Terminal Helix Residues 502-509. To Be Published.
Page generated: Wed Aug 14 18:10:18 2024
Last articles
Mg in 2DFTMg in 2DKG
Mg in 2DH4
Mg in 2DGN
Mg in 2DES
Mg in 2DDT
Mg in 2DEI
Mg in 2DEJ
Mg in 2DE3
Mg in 2DDX
