Magnesium in PDB 3th5: Crystal Structure of Wild-Type RAC1

The structure of Crystal Structure of Wild-Type RAC1, PDB code: 3th5 was solved by B.H.Ha, T.J.Boggon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	40.925, 97.851, 51.733, 90.00, 96.59, 90.00
R / Rfree (%)	22.9 / 26.4

The binding sites of Magnesium atom in the Crystal Structure of Wild-Type RAC1 (pdb code 3th5). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Wild-Type RAC1, PDB code: 3th5:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Wild-Type RAC1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Wild-Type RAC1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1002 b:52.0 occ:1.00 OG1 A:THR35 1.8 75.6 1.0 O2G A:GNP1001 1.9 48.6 1.0 O2B A:GNP1001 2.0 45.8 1.0 O A:HOH188 2.0 61.8 1.0 OG1 A:THR17 2.1 53.7 1.0 O A:HOH187 2.4 57.3 1.0 CB A:THR35 3.1 77.8 1.0 CB A:THR17 3.1 53.7 1.0 PG A:GNP1001 3.2 49.1 1.0 PB A:GNP1001 3.3 46.8 1.0 N3B A:GNP1001 3.4 47.7 1.0 N A:THR35 3.6 83.5 1.0 O2A A:GNP1001 3.8 47.6 1.0 N A:THR17 3.9 46.4 1.0 CA A:THR35 3.9 83.4 1.0 OD2 A:ASP57 4.0 56.0 1.0 CA A:THR17 4.1 49.5 1.0 CG2 A:THR35 4.1 78.2 1.0 O1G A:GNP1001 4.2 48.8 1.0 CG2 A:THR17 4.2 58.2 1.0 O3A A:GNP1001 4.3 46.6 1.0 O1B A:GNP1001 4.3 45.6 1.0 O3G A:GNP1001 4.3 50.0 1.0 PA A:GNP1001 4.4 47.2 1.0 OD1 A:ASP57 4.4 50.7 1.0 O A:ILE33 4.5 87.8 1.0 O1A A:GNP1001 4.5 47.4 1.0 CG A:ASP57 4.6 54.1 1.0 C A:PRO34 4.7 88.2 1.0 O A:THR58 4.8 53.6 1.0 CB A:LYS16 4.9 41.0 1.0 CA A:PRO34 5.0 88.3 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Wild-Type RAC1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Wild-Type RAC1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1002 b:49.5 occ:1.00 OG1 B:THR17 1.9 58.6 1.0 O B:HOH186 1.9 61.4 1.0 O2B B:GNP1001 2.0 50.1 1.0 O2G B:GNP1001 2.0 52.9 1.0 OG1 B:THR35 2.2 84.3 1.0 O B:HOH184 2.3 64.3 1.0 CB B:THR35 3.0 85.7 1.0 CB B:THR17 3.1 58.5 1.0 PG B:GNP1001 3.2 52.9 1.0 PB B:GNP1001 3.3 51.2 1.0 N3B B:GNP1001 3.5 52.0 1.0 OD2 B:ASP57 3.6 61.7 1.0 N B:THR17 3.7 50.3 1.0 CG2 B:THR35 3.7 84.4 1.0 CA B:THR17 3.9 53.9 1.0 OD1 B:ASP57 4.0 57.0 1.0 O1G B:GNP1001 4.0 52.3 1.0 O2A B:GNP1001 4.1 52.6 1.0 O1B B:GNP1001 4.2 50.2 1.0 CG B:ASP57 4.2 59.6 1.0 CG2 B:THR17 4.2 63.2 1.0 O3A B:GNP1001 4.3 50.8 1.0 CA B:THR35 4.4 92.5 1.0 O B:THR58 4.5 58.5 1.0 O3G B:GNP1001 4.5 54.9 1.0 O1A B:GNP1001 4.5 52.6 1.0 PA B:GNP1001 4.5 51.9 1.0 N B:THR35 4.5 94.5 1.0 CB B:LYS16 4.7 44.2 1.0 C B:LYS16 4.8 46.8 1.0 CE B:LYS16 4.8 46.7 1.0

M.Krauthammer, Y.Kong, B.H.Ha, P.Evans, A.Bacchiocchi, J.P.Mccusker, E.Cheng, M.J.Davis, G.Goh, M.Choi, S.Ariyan, D.Narayan, K.Dutton-Regester, A.Capatana, E.C.Holman, M.Bosenberg, M.Sznol, H.M.Kluger, D.E.Brash, D.F.Stern, M.A.Materin, R.S.Lo, S.Mane, S.Ma, K.K.Kidd, N.K.Hayward, R.P.Lifton, J.Schlessinger, T.J.Boggon, R.Halaban. Exome Sequencing Identifies Recurrent Somatic RAC1 Mutations in Melanoma. Nat.Genet. V. 44 1006 2012.
ISSN: ISSN 1061-4036
PubMed: 22842228
DOI: 10.1038/NG.2359