Atomistry » Magnesium » PDB 4la7-4lj9 » 4lgy
Atomistry »
  Magnesium »
    PDB 4la7-4lj9 »
      4lgy »

Magnesium in PDB 4lgy: Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis

Enzymatic activity of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis

All present enzymatic activity of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis:
6.3.5.3;

Protein crystallography data

The structure of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis, PDB code: 4lgy was solved by A.S.Tanwar, V.D.Goyal, D.Choudhary, S.Panjikar, R.Anand, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.50 / 1.48
Space group P 65
Cell size a, b, c (Å), α, β, γ (°) 146.329, 146.329, 140.841, 90.00, 90.00, 120.00
R / Rfree (%) 14.2 / 16.6

Other elements in 4lgy:

The structure of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis also contains other interesting chemical elements:

Chlorine (Cl) 6 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis (pdb code 4lgy). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 7 binding sites of Magnesium where determined in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis, PDB code: 4lgy:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7;

Magnesium binding site 1 out of 7 in 4lgy

Go back to Magnesium Binding Sites List in 4lgy
Magnesium binding site 1 out of 7 in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1302

b:5.6
occ:1.00
 O1B A:ADP1301 2.0 6.2 1.0
OD1 A:ASP884 2.0 6.0 1.0
OD1 A:ASP679 2.1 6.1 1.0
OD1 A:ASN722 2.1 5.0 1.0
O A:HOH2425 2.1 6.8 1.0
O A:HOH2423 2.2 6.3 1.0
CG A:ASP884 3.0 6.0 1.0
CG A:ASP679 3.1 7.5 1.0
CG A:ASN722 3.1 5.4 1.0
PB A:ADP1301 3.2 6.0 1.0
OD2 A:ASP884 3.3 7.2 1.0
ND2 A:ASN722 3.6 6.0 1.0
O3B A:ADP1301 3.7 6.2 1.0
O2B A:ADP1301 3.8 6.2 1.0
CB A:ASP679 3.8 5.7 1.0
OD2 A:ASP679 3.9 7.2 1.0
O A:HOH1430 3.9 6.4 1.0
OG A:SER886 4.1 8.0 1.0
O A:HOH1742 4.2 14.2 1.0
NE2 A:HIS883 4.2 8.3 1.0
CA A:ASP679 4.3 6.2 1.0
CD2 A:HIS883 4.4 3.9 1.0
O A:ASP884 4.4 7.6 1.0
CB A:ASP884 4.4 5.3 1.0
O3A A:ADP1301 4.4 6.3 1.0
O A:HOH1428 4.4 6.9 1.0
CB A:ASN722 4.5 5.8 1.0
N A:ASP884 4.6 5.6 1.0
C A:ASP884 4.8 6.5 1.0
CA A:ASN722 4.8 5.2 1.0
OE2 A:GLU718 4.8 7.6 1.0
CA A:ASP884 4.8 5.9 1.0
O A:ASP679 4.9 7.3 1.0
CB A:SER886 5.0 7.7 1.0

Magnesium binding site 2 out of 7 in 4lgy

Go back to Magnesium Binding Sites List in 4lgy
Magnesium binding site 2 out of 7 in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1303

b:7.1
occ:1.00
 OE2 A:GLU718 2.0 7.6 1.0
O3B A:ADP1301 2.0 6.2 1.0
O A:HOH2422 2.0 9.9 1.0
O A:HOH2424 2.1 9.0 1.0
O A:HOH2427 2.1 7.8 1.0
O A:HOH1420 2.1 8.4 1.0
CD A:GLU718 3.1 8.7 1.0
PB A:ADP1301 3.3 6.0 1.0
OE1 A:GLU718 3.5 10.2 1.0
O2B A:ADP1301 3.6 6.2 1.0
O A:HOH1588 3.9 9.6 1.0
O A:HOH2423 4.0 6.3 1.0
ND2 A:ASN722 4.1 6.0 1.0
O3A A:ADP1301 4.1 6.3 1.0
O A:HOH1793 4.2 13.5 1.0
O1A A:ADP1301 4.3 8.5 1.0
OE2 A:GLU699 4.3 14.4 1.0
OD2 A:ASP887 4.3 11.6 1.0
O A:ILE697 4.4 6.8 1.0
CG A:GLU718 4.4 8.0 1.0
O1B A:ADP1301 4.5 6.2 1.0
OG A:SER886 4.5 8.0 1.0
CB A:SER886 4.7 7.7 1.0
PA A:ADP1301 4.8 6.6 1.0
O A:HOH2426 4.9 7.9 1.0
O A:GLU699 4.9 8.4 1.0

Magnesium binding site 3 out of 7 in 4lgy

Go back to Magnesium Binding Sites List in 4lgy
Magnesium binding site 3 out of 7 in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1304

b:6.7
occ:1.00
 O2B A:ADP1301 2.0 6.2 1.0
O2A A:ADP1301 2.0 6.3 1.0
O A:HOH1404 2.1 5.9 1.0
O A:HOH2426 2.1 7.9 1.0
O A:HOH1428 2.1 6.9 1.0
O A:HOH2421 2.2 7.3 1.0
PA A:ADP1301 3.2 6.6 1.0
PB A:ADP1301 3.3 6.0 1.0
O3A A:ADP1301 3.5 6.3 1.0
O1A A:ADP1301 3.9 8.5 1.0
O A:HOH1420 4.0 8.4 1.0
O A:HOH1568 4.0 10.4 1.0
OG A:SER886 4.1 8.0 1.0
O A:HOH2425 4.1 6.8 1.0
O1B A:ADP1301 4.1 6.2 1.0
OE1 A:GLU896 4.2 7.6 1.0
OE2 A:GLU896 4.2 7.0 1.0
O A:HOH1430 4.3 6.4 1.0
O3B A:ADP1301 4.4 6.2 1.0
O5' A:ADP1301 4.5 5.3 1.0
O A:HOH1619 4.5 12.6 1.0
O A:THR645 4.5 7.1 1.0
OD2 A:ASP887 4.6 11.6 1.0
O A:VAL646 4.6 6.4 1.0
CD A:GLU896 4.7 7.7 1.0
O A:ASP887 4.7 7.3 1.0
C5' A:ADP1301 4.8 6.1 1.0
CB A:ASP887 4.9 8.3 1.0

Magnesium binding site 4 out of 7 in 4lgy

Go back to Magnesium Binding Sites List in 4lgy
Magnesium binding site 4 out of 7 in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1337

b:27.1
occ:1.00
 O A:HOH3007 2.2 20.2 1.0
O A:HOH1470 2.7 10.5 1.0
O A:HOH2998 2.9 8.9 1.0
O A:PHE1169 3.2 8.2 1.0
O A:HOH3005 3.4 20.9 1.0
O A:HOH1448 3.9 7.2 1.0
C A:PHE1169 4.1 5.8 1.0
O A:HOH2669 4.3 36.1 1.0
O A:HOH3000 4.4 16.1 1.0
CB A:ARG1168 4.4 6.3 1.0
N A:PHE1169 4.4 5.4 1.0
CA A:SER1170 4.5 5.6 1.0
CD A:ARG1168 4.5 6.9 1.0
O A:HOH3003 4.7 21.2 1.0
O A:HOH1481 4.7 11.0 1.0
N A:SER1170 4.7 5.8 1.0
OG A:SER1170 4.7 7.8 1.0
O A:PRO1234 4.8 6.8 1.0
CG A:PRO1234 4.8 6.7 1.0
CG A:GLN674 4.9 5.4 1.0
CA A:PHE1169 4.9 5.5 1.0
CB A:GLN674 4.9 4.9 1.0
CG A:ARG1168 5.0 6.8 1.0

Magnesium binding site 5 out of 7 in 4lgy

Go back to Magnesium Binding Sites List in 4lgy
Magnesium binding site 5 out of 7 in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1338

b:31.6
occ:1.00
 OG1 A:THR1232 2.8 12.7 1.0
O A:HOH2483 3.1 18.4 1.0
O1 A:GOL1327 3.3 16.2 1.0
N A:THR1232 3.4 7.3 1.0
C A:GLU1231 3.5 7.6 1.0
CA A:THR1232 3.7 7.3 1.0
CB A:GLU1231 3.8 8.9 1.0
O A:GLU1231 3.8 8.8 1.0
C1 A:GOL1327 3.9 24.4 1.0
CB A:THR1232 3.9 8.4 1.0
CA A:GLU1231 4.0 7.8 1.0
N A:GLU1231 4.2 8.7 1.0
O A:HOH2154 4.6 23.8 1.0
OE1 A:GLN1004 4.7 17.2 1.0
CG2 A:THR1232 4.8 9.4 1.0
OG1 A:THR1230 5.0 11.4 1.0

Magnesium binding site 6 out of 7 in 4lgy

Go back to Magnesium Binding Sites List in 4lgy
Magnesium binding site 6 out of 7 in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1339

b:39.2
occ:1.00
 O A:HOH1632 2.6 17.6 1.0
O A:HOH2204 2.9 41.8 1.0
O A:PHE1112 3.3 18.6 1.0
CB A:ASN1113 3.6 13.5 1.0
OD1 A:ASN1113 3.6 19.9 1.0
CA A:ASN1113 3.6 12.3 1.0
C A:PHE1112 3.8 14.5 1.0
C A:CYS98 3.8 16.6 1.0
N A:ASN1113 3.9 12.2 1.0
O A:CYS98 3.9 19.5 1.0
N A:GLY99 3.9 14.3 1.0
CA A:GLY99 4.0 17.1 1.0
CG A:ASN1113 4.1 15.5 1.0
O A:ASN97 4.4 15.4 1.0
CA A:CYS98 4.4 12.6 1.0
O A:HOH1828 4.7 24.1 1.0
O A:HOH1882 4.7 21.7 1.0
CB A:PHE1112 4.8 12.3 1.0
CA A:PHE1112 4.9 11.0 1.0

Magnesium binding site 7 out of 7 in 4lgy

Go back to Magnesium Binding Sites List in 4lgy
Magnesium binding site 7 out of 7 in the Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1340

b:26.8
occ:1.00
 O A:ALA875 3.0 8.7 1.0
ND1 A:HIS813 3.1 9.6 1.0
NE2 A:GLN727 3.2 9.4 1.0
CE1 A:HIS813 3.2 9.8 1.0
OE1 A:GLN727 3.4 10.9 1.0
O A:HOH1616 3.6 12.6 1.0
CD A:GLN727 3.7 8.9 1.0
CA A:ALA875 3.9 7.3 1.0
C A:ALA875 3.9 6.8 1.0
O A:HOH2983 4.3 33.6 1.0
CB A:ALA875 4.4 8.3 1.0
CD A:ARG877 4.4 16.4 1.0
CG A:HIS813 4.4 7.5 1.0
NE2 A:HIS813 4.5 11.2 1.0
O A:VAL874 5.0 6.9 1.0

Reference:

A.S.Tanwar, V.D.Goyal, D.Choudhary, S.Panjikar, R.Anand. Importance of Hydrophobic Cavities in Allosteric Regulation of Formylglycinamide Synthetase: Insight From Xenon Trapping and Statistical Coupling Analysis Plos One V. 8 77781 2013.
ISSN: ESSN 1932-6203
PubMed: 24223728
DOI: 10.1371/JOURNAL.PONE.0077781
Page generated: Mon Aug 19 17:43:26 2024

Last articles

Mg in 4JHD
Mg in 4JH6
Mg in 4JH8
Mg in 4JH7
Mg in 4JH3
Mg in 4JH5
Mg in 4JF2
Mg in 4JH2
Mg in 4JH1
Mg in 4JEJ
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy