Magnesium in PDB 4txy: Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog

All present enzymatic activity of Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog:
2.7.7.86;

The structure of Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog, PDB code: 4txy was solved by P.J.Kranzusch, A.S.Y.Lee, S.C.Wilson, M.S.Solovykh, R.E.Vance, J.M.Berger, J.A.Doudna, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.12 / 3.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	70.167, 59.116, 102.539, 90.00, 95.48, 90.00
R / Rfree (%)	22.5 / 25

The binding sites of Magnesium atom in the Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog (pdb code 4txy). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog, PDB code: 4txy:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:72.9 occ:1.00 OD2 A:ASP194 2.1 39.6 1.0 OD2 A:ASP132 2.3 51.2 1.0 OD1 A:ASP132 2.3 51.9 1.0 OD1 A:ASP134 2.4 48.5 1.0 CG A:ASP132 2.6 50.4 1.0 OD2 A:ASP134 2.9 48.0 1.0 CG A:ASP134 2.9 47.6 1.0 CG A:ASP194 3.3 38.6 1.0 CB A:ASP194 4.0 38.3 1.0 CB A:ASP132 4.1 47.4 1.0 CE1 A:HIS192 4.1 41.6 1.0 NH2 A:ARG183 4.3 48.4 1.0 OD1 A:ASP194 4.3 37.9 1.0 CB A:ASP134 4.4 46.6 1.0 NE2 A:HIS192 4.9 42.5 1.0 CA A:ASP132 4.9 46.5 1.0 N A:ASP134 5.0 45.9 1.0 CA A:ASP134 5.0 46.5 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Vibrio Cholerae Dncv Cyclic Amp-Gmp Synthase, A Prokaryotic Cgas Homolog within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg501 b:71.8 occ:1.00 OD1 B:ASP132 2.3 48.1 1.0 OD2 B:ASP194 2.3 32.0 1.0 OD1 B:ASP134 2.3 50.7 1.0 OD2 B:ASP132 2.4 48.5 1.0 CG B:ASP132 2.6 48.1 1.0 OD2 B:ASP134 2.8 51.6 1.0 CG B:ASP134 2.9 50.6 1.0 CG B:ASP194 3.5 32.6 1.0 CB B:ASP132 4.2 47.5 1.0 CB B:ASP194 4.2 33.0 1.0 NE2 B:HIS192 4.3 37.8 1.0 NH2 B:ARG183 4.4 45.8 1.0 CB B:ASP134 4.4 49.5 1.0 OD1 B:ASP194 4.5 33.2 1.0 N B:ASP134 4.9 46.8 1.0 CA B:ASP132 4.9 46.2 1.0

P.J.Kranzusch, A.S.Lee, S.C.Wilson, M.S.Solovykh, R.E.Vance, J.M.Berger, J.A.Doudna. Structure-Guided Reprogramming of Human Cgas Dinucleotide Linkage Specificity. Cell V. 158 1011 2014.
ISSN: ISSN 1097-4172
PubMed: 25131990
DOI: 10.1016/J.CELL.2014.07.028