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Atomistry » Magnesium » PDB 7k16-7kee » 7k7l » |
Magnesium in PDB 7k7l: Structure of A Hit For G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor For the Potential Treatment of Heart FailureEnzymatic activity of Structure of A Hit For G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor For the Potential Treatment of Heart Failure
All present enzymatic activity of Structure of A Hit For G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor For the Potential Treatment of Heart Failure:
2.7.11.15; Protein crystallography data
The structure of Structure of A Hit For G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor For the Potential Treatment of Heart Failure, PDB code: 7k7l
was solved by
J.C.Spurlino,
C.Milligan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of A Hit For G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor For the Potential Treatment of Heart Failure
(pdb code 7k7l). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of A Hit For G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor For the Potential Treatment of Heart Failure, PDB code: 7k7l: Magnesium binding site 1 out of 1 in 7k7lGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Structure of A Hit For G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor For the Potential Treatment of Heart Failure
![]() Mono view ![]() Stereo pair view
Reference:
G.Xu,
M.D.Gaul,
Z.Liu,
R.L.Desjarlais,
J.Qi,
W.Wang,
D.Krosky,
I.Petrounia,
C.M.Milligan,
A.Hermans,
H.R.Lu,
D.Z.Huang,
J.Z.Xu,
J.C.Spurlino.
Hit-to-Lead Optimization and Discovery of A Potent, and Orally Bioavailable G Protein Coupled Receptor Kinase 2 (GRK2) Inhibitor. Bioorg.Med.Chem.Lett. V. 30 27602 2020.
Page generated: Wed Oct 2 22:09:23 2024
ISSN: ESSN 1464-3405 PubMed: 33038544 DOI: 10.1016/J.BMCL.2020.127602 |
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