Magnesium in PDB 7z0f: Cpap:S-Tubulin:IIH5 Alpharep Complex

The structure of Cpap:S-Tubulin:IIH5 Alpharep Complex, PDB code: 7z0f was solved by B.Gigant, V.Campanacci, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.79 / 2.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	54.28, 86.71, 137.61, 90, 96.61, 90
R / Rfree (%)	22.2 / 27.3

The binding sites of Magnesium atom in the Cpap:S-Tubulin:IIH5 Alpharep Complex (pdb code 7z0f). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cpap:S-Tubulin:IIH5 Alpharep Complex, PDB code: 7z0f:

Magnesium binding site 1 out of 1 in the Cpap:S-Tubulin:IIH5 Alpharep Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cpap:S-Tubulin:IIH5 Alpharep Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg601 b:72.0 occ:1.00 O A:HOH716 1.9 65.8 1.0 O A:HOH713 1.9 82.2 1.0 O A:HOH721 2.0 84.1 1.0 O2G A:GTP600 2.2 73.5 1.0 O1B A:GTP600 2.5 71.8 1.0 O A:HOH703 2.5 69.0 1.0 PG A:GTP600 3.5 73.4 1.0 PB A:GTP600 3.6 71.9 1.0 NZ B:LYS254 3.7 99.8 1.0 O3B A:GTP600 3.9 72.9 1.0 O1G A:GTP600 4.0 73.5 1.0 O3A A:GTP600 4.0 72.3 1.0 OE2 A:GLU71 4.0 106.0 1.0 CB A:GLN11 4.1 64.9 1.0 O1A A:GTP600 4.3 71.7 1.0 OD2 A:ASP69 4.3 71.7 1.0 OE1 A:GLN11 4.3 79.8 1.0 OD2 A:ASP98 4.4 91.9 1.0 OD1 A:ASP69 4.4 73.0 1.0 N A:GLN11 4.5 62.2 1.0 CD A:GLU71 4.6 103.6 1.0 O3G A:GTP600 4.6 73.1 1.0 CB A:ASP98 4.7 86.2 1.0 PA A:GTP600 4.8 72.1 1.0 CG A:ASP69 4.8 71.5 1.0 CG A:ASP98 4.9 89.7 1.0 CA A:GLN11 4.9 63.5 1.0 OE1 A:GLU71 5.0 106.9 1.0 O2B A:GTP600 5.0 71.2 1.0 CD A:GLN11 5.0 75.3 1.0 CE B:LYS254 5.0 98.2 1.0

V.Campanacci, A.Urvoas, L.Ammar Khodja, M.Aumont-Nicaise, M.Noiray, S.Lachkar, P.A.Curmi, P.Minard, B.Gigant. Structural Convergence For Tubulin Binding of Cpap and Vinca Domain Microtubule Inhibitors. Proc.Natl.Acad.Sci.Usa V. 119 98119 2022.
ISSN: ESSN 1091-6490
PubMed: 35507869
DOI: 10.1073/PNAS.2120098119