Magnesium in PDB 7z0g: Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group

The structure of Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group, PDB code: 7z0g was solved by B.Gigant, V.Campanacci, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.54 / 3.49
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	57.11, 75.9, 151.32, 96.19, 98.28, 111.6
R / Rfree (%)	23.7 / 27.6

The binding sites of Magnesium atom in the Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group (pdb code 7z0g). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group, PDB code: 7z0g:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg601 b:38.6 occ:1.00 O1B A:GTP600 2.6 106.7 1.0 O2G A:GTP600 2.7 108.6 1.0 O1G A:GTP600 3.0 108.2 1.0 PG A:GTP600 3.3 108.2 1.0 NZ B:LYS254 3.5 97.9 1.0 OD2 A:ASP98 3.5 115.2 1.0 PB A:GTP600 3.6 106.3 1.0 OE1 A:GLU71 3.7 116.9 1.0 O3B A:GTP600 3.9 107.2 1.0 O3A A:GTP600 3.9 106.6 1.0 OE1 A:GLN11 4.1 94.6 1.0 CB A:GLN11 4.1 79.3 1.0 O1A A:GTP600 4.4 107.2 1.0 CE B:LYS254 4.5 95.4 1.0 CG A:ASP98 4.6 112.0 1.0 OD1 A:ASP69 4.7 96.2 1.0 CD A:GLU71 4.7 116.2 1.0 OD2 A:ASP69 4.7 96.5 1.0 N A:GLN11 4.7 77.6 1.0 O3G A:GTP600 4.7 108.7 1.0 CB A:ASP98 4.8 102.5 1.0 PA A:GTP600 4.9 106.5 1.0

Magnesium binding site 2 out of 2 in the Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cpap:Tubulin:IE5 Alpharep Complex P1 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ R:Mg601 b:38.7 occ:1.00 O1B R:GTP600 2.2 105.3 1.0 OE1 R:GLU71 2.6 109.7 1.0 O1G R:GTP600 3.0 108.0 1.0 O2G R:GTP600 3.1 108.3 1.0 PB R:GTP600 3.4 105.4 1.0 PG R:GTP600 3.5 107.8 1.0 CD R:GLU71 3.5 108.7 1.0 CG R:GLU71 3.8 99.5 1.0 CB R:GLN11 3.8 84.1 1.0 O3B R:GTP600 3.8 106.5 1.0 OD2 R:ASP98 3.9 110.7 1.0 O3A R:GTP600 3.9 105.2 1.0 OD2 R:ASP69 4.0 83.7 1.0 N R:GLN11 4.2 82.1 1.0 OD1 R:ASP69 4.2 82.5 1.0 OE1 R:GLN11 4.2 98.3 1.0 O1A R:GTP600 4.5 104.8 1.0 CG R:ASP69 4.5 82.0 1.0 CA R:GLN11 4.6 81.8 1.0 OE2 R:GLU71 4.6 111.7 1.0 O2B R:GTP600 4.7 105.0 1.0 CB R:ASP98 4.8 99.7 1.0 CG R:ASP98 4.8 108.7 1.0 PA R:GTP600 4.9 104.6 1.0 CG2 R:VAL74 4.9 94.5 1.0 CG R:GLN11 4.9 88.3 1.0 O3G R:GTP600 5.0 108.0 1.0

V.Campanacci, A.Urvoas, L.Ammar Khodja, M.Aumont-Nicaise, M.Noiray, S.Lachkar, P.A.Curmi, P.Minard, B.Gigant. Structural Convergence For Tubulin Binding of Cpap and Vinca Domain Microtubule Inhibitors. Proc.Natl.Acad.Sci.Usa V. 119 98119 2022.
ISSN: ESSN 1091-6490
PubMed: 35507869
DOI: 10.1073/PNAS.2120098119