Magnesium in PDB 8k0g: Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub.

All present enzymatic activity of Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub.:
3.4.25.1;

The binding sites of Magnesium atom in the Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub. (pdb code 8k0g). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub., PDB code: 8k0g:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:24.0 occ:1.00 OG1 A:THR223 2.0 21.5 1.0 O3G A:ATP501 2.1 34.7 1.0 O1B A:ATP501 2.2 34.7 1.0 CB A:THR223 2.9 21.5 1.0 PG A:ATP501 3.2 34.7 1.0 PB A:ATP501 3.3 34.7 1.0 O3B A:ATP501 3.3 34.7 1.0 O2G A:ATP501 3.7 34.7 1.0 CG2 A:THR223 3.7 21.5 1.0 O1A A:ATP501 4.0 34.7 1.0 O3A A:ATP501 4.1 34.7 1.0 CA A:THR223 4.1 21.5 1.0 N A:THR223 4.1 21.5 1.0 PA A:ATP501 4.5 34.7 1.0 O1G A:ATP501 4.5 34.7 1.0 O2B A:ATP501 4.6 34.7 1.0 O2A A:ATP501 4.7 34.7 1.0 NZ A:LYS222 4.9 16.8 1.0

Magnesium binding site 2 out of 4 in the Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub. within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg502 b:78.1 occ:1.00 O2B B:ATP501 1.9 30.9 1.0 O2G B:ATP501 2.5 30.9 1.0 CG2 B:THR233 2.6 19.5 1.0 PB B:ATP501 3.2 30.9 1.0 O3B B:ATP501 3.6 30.9 1.0 PG B:ATP501 3.7 30.9 1.0 O3A B:ATP501 3.9 30.9 1.0 CB B:THR233 4.0 19.5 1.0 OD2 B:ASP285 4.1 37.6 1.0 OG1 B:THR233 4.2 19.5 1.0 O1B B:ATP501 4.4 30.9 1.0 O1G B:ATP501 4.6 30.9 1.0 O3G B:ATP501 4.7 30.9 1.0 OD1 B:ASP285 4.7 37.6 1.0 N B:THR233 4.8 19.5 1.0 O C:ASP281 4.8 27.8 1.0 CG B:ASP285 4.9 37.6 1.0 OE2 B:GLU286 4.9 38.7 1.0 O1A B:ATP501 4.9 30.9 1.0 CA B:THR233 5.0 19.5 1.0 NH2 C:ARG310 5.0 22.9 1.0

Magnesium binding site 3 out of 4 in the Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub. within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg502 b:54.5 occ:1.00 O3B D:ADP501 1.9 48.6 1.0 OG1 D:THR213 2.8 39.1 1.0 PB D:ADP501 3.0 48.6 1.0 O1B D:ADP501 3.2 48.6 1.0 O2B D:ADP501 4.0 48.6 1.0 O3A D:ADP501 4.1 48.6 1.0 CB D:THR213 4.1 39.1 1.0 CG D:LYS212 4.4 42.3 1.0 O1A D:ADP501 4.5 48.6 1.0 O2A D:ADP501 4.6 48.6 1.0 PA D:ADP501 4.6 48.6 1.0 N D:THR213 4.7 39.1 1.0 CD D:LYS212 4.9 42.3 1.0

Magnesium binding site 4 out of 4 in the Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Cryo-Em Structure of Human 26S Rp (Ed State) Bound to K11/K48-Branched Ubiquitin (Ub) Chain Composed of Four Ub. within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg502 b:43.5 occ:1.00 O1B C:ADP501 1.9 78.1 1.0 O3B C:ADP501 2.3 78.1 1.0 PB C:ADP501 2.3 78.1 1.0 OG1 C:THR197 3.1 24.2 1.0 O2B C:ADP501 3.1 78.1 1.0 O3A C:ADP501 3.8 78.1 1.0 O1A C:ADP501 3.8 78.1 1.0 OE2 C:GLU250 4.1 46.2 1.0 PA C:ADP501 4.4 78.1 1.0 CB C:THR197 4.4 24.2 1.0 N C:THR197 4.8 24.2 1.0 O2A C:ADP501 4.9 78.1 1.0 CB C:LYS196 5.0 25.0 1.0

P.Draczkowski, S.T.D.Hsu, Y.S.Wang. Cryo-Em Structure of Human 26S Proteasomal Rp Subcomplex Bound with Branched Ub Chain. To Be Published.