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Atomistry » Magnesium » PDB 1q3b-1qc1 » 1q6s » |
Magnesium in PDB 1q6s: The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9Enzymatic activity of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9
All present enzymatic activity of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9:
3.1.3.48; Protein crystallography data
The structure of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9, PDB code: 1q6s
was solved by
G.Scapin,
S.B.Patel,
J.W.Becker,
Q.Wang,
C.Desponts,
D.Waddleton,
K.Skorey,
W.Cromlish,
C.Bayly,
M.Therien,
J.Y.Gauthier,
C.S.Li,
C.K.Lau,
C.Ramachandran,
B.P.Kennedy,
E.Asante-Appiah,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1q6s:
The structure of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9
(pdb code 1q6s). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9, PDB code: 1q6s: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 1q6sGo back to Magnesium Binding Sites List in 1q6s
Magnesium binding site 1 out
of 2 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 1q6sGo back to Magnesium Binding Sites List in 1q6s
Magnesium binding site 2 out
of 2 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 9
Mono view Stereo pair view
Reference:
G.Scapin,
S.B.Patel,
J.W.Becker,
Q.Wang,
C.Desponts,
D.Waddleton,
K.Skorey,
W.Cromlish,
C.Bayly,
M.Therien,
J.Y.Gauthier,
C.S.Li,
C.K.Lau,
C.Ramachandran,
B.P.Kennedy,
E.Asante-Appiah.
The Structural Basis For the Selectivity of Benzotriazole Inhibitors of PTP1B Biochemistry V. 42 11451 2003.
Page generated: Tue Aug 13 11:07:48 2024
ISSN: ISSN 0006-2960 PubMed: 14516196 DOI: 10.1021/BI035098J |
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