Magnesium in PDB 2cfs: Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase

All present enzymatic activity of Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase:
3.1.3.74;

The structure of Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase, PDB code: 2cfs was solved by B.S.Kang, H.J.Cho, K.J.Kim, O.S.Kwon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.64 / 2.4
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	54.631, 54.631, 213.985, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 25.7

The binding sites of Magnesium atom in the Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase (pdb code 2cfs). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase, PDB code: 2cfs:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1296 b:19.1 occ:1.00 O A:HOH2006 1.9 16.9 1.0 OD2 A:ASP25 2.0 16.9 1.0 O A:HOH2078 2.0 15.0 1.0 O A:HOH2076 2.1 20.2 1.0 OD1 A:ASP238 2.1 22.8 1.0 O A:ASP27 2.3 15.7 1.0 CG A:ASP25 3.0 18.4 1.0 CG A:ASP238 3.2 21.1 1.0 OD1 A:ASP25 3.3 20.9 1.0 C A:ASP27 3.4 16.9 0.5 OD2 A:ASP238 3.5 21.9 1.0 OD2 A:ASP243 3.9 24.0 1.0 N A:ASP27 4.2 18.1 1.0 CA A:ASP27 4.3 17.9 1.0 CB A:ASP25 4.3 19.3 1.0 O A:HOH2059 4.4 30.2 1.0 CB A:ASP238 4.4 21.5 1.0 N A:GLY28 4.4 16.9 1.0 CG2 A:VAL29 4.5 15.7 1.0 CB A:ASP27 4.6 18.3 0.5 CA A:GLY28 4.6 17.8 1.0 N A:ASP238 4.6 21.0 1.0 CB A:ASP27 4.7 17.7 0.5 O A:HOH2020 4.7 19.5 1.0 C A:CYS26 4.8 17.9 1.0 CG A:ASP243 4.9 25.1 1.0 N A:CYS26 4.9 19.1 1.0 CB A:ARG239 4.9 25.6 1.0 O A:HOH2007 5.0 17.5 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1297 b:16.2 occ:1.00 NE A:ARG263 3.0 27.0 1.0 O A:HOH2082 3.1 30.6 1.0 N A:LEU264 3.2 29.7 1.0 CD A:ARG263 3.6 29.0 1.0 CA A:ARG263 3.7 28.2 1.0 CD2 A:LEU258 3.9 23.6 1.0 CB A:LEU264 3.9 29.9 1.0 CB A:ARG263 4.0 28.4 1.0 C A:ARG263 4.0 29.2 1.0 CZ A:ARG263 4.0 25.6 1.0 NH2 A:ARG263 4.1 23.6 1.0 CA A:LEU264 4.2 30.4 1.0 CG A:ARG263 4.4 27.2 1.0 CG A:LEU258 4.5 25.0 1.0 CD1 A:LEU258 4.5 24.5 1.0 CB A:LEU258 4.5 22.6 1.0 O A:SER262 4.9 26.1 1.0 N A:GLU265 4.9 33.2 1.0

B.S.Kang, H.J.Cho, K.J.Kim, O.S.Kwon. Crystal Structure of Human Pyridoxal 5'-Phosphate Phosphatase To Be Published.