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Atomistry » Magnesium » PDB 4qpz-4qwg » 4qtd | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 4qpz-4qwg » 4qtd » |
Magnesium in PDB 4qtd: Structure of Human JNK1 in Complex with SCH772984 and the Amppnp- Hydrolysed Triphosphate Revealing the Second Type-I Binding ModeEnzymatic activity of Structure of Human JNK1 in Complex with SCH772984 and the Amppnp- Hydrolysed Triphosphate Revealing the Second Type-I Binding Mode
All present enzymatic activity of Structure of Human JNK1 in Complex with SCH772984 and the Amppnp- Hydrolysed Triphosphate Revealing the Second Type-I Binding Mode:
2.7.11.24; Protein crystallography data
The structure of Structure of Human JNK1 in Complex with SCH772984 and the Amppnp- Hydrolysed Triphosphate Revealing the Second Type-I Binding Mode, PDB code: 4qtd
was solved by
A.Chaikuad,
T.Keates,
F.Von Delft,
C.H.Arrowsmith,
A.M.Edwards,
C.Bountra,
S.Knapp,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of Human JNK1 in Complex with SCH772984 and the Amppnp- Hydrolysed Triphosphate Revealing the Second Type-I Binding Mode
(pdb code 4qtd). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Human JNK1 in Complex with SCH772984 and the Amppnp- Hydrolysed Triphosphate Revealing the Second Type-I Binding Mode, PDB code: 4qtd: Magnesium binding site 1 out of 1 in 4qtdGo back to Magnesium Binding Sites List in 4qtd
Magnesium binding site 1 out
of 1 in the Structure of Human JNK1 in Complex with SCH772984 and the Amppnp- Hydrolysed Triphosphate Revealing the Second Type-I Binding Mode
Mono view Stereo pair view
Reference:
A.Chaikuad,
E.M C Tacconi,
J.Zimmer,
Y.Liang,
N.S.Gray,
M.Tarsounas,
S.Knapp.
A Unique Inhibitor Binding Site in ERK1/2 Is Associated with Slow Binding Kinetics. Nat.Chem.Biol. V. 10 853 2014.
Page generated: Mon Dec 14 19:24:25 2020
ISSN: ISSN 1552-4450 PubMed: 25195011 DOI: 10.1038/NCHEMBIO.1629 |
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