Magnesium in PDB 5flx: Mammalian 40S Hcv-Ires Complex

All present enzymatic activity of Mammalian 40S Hcv-Ires Complex:
4.2.99.18;

The structure of Mammalian 40S Hcv-Ires Complex also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 70; Page 8, Binding sites: 71 - 74;

Binding sites:

The binding sites of Magnesium atom in the Mammalian 40S Hcv-Ires Complex (pdb code 5flx). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 74 binding sites of Magnesium where determined in the Mammalian 40S Hcv-Ires Complex, PDB code: 5flx:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1901 b:20.0 occ:1.00 O4 1:U1691 4.0 20.0 1.0 N4 1:C1205 4.1 20.0 1.0 N6 1:A1208 4.5 20.0 1.0 O4 1:U1692 4.6 20.0 1.0 O6 1:G1206 4.7 20.0 1.0 C4 1:C1205 5.0 20.0 1.0

Magnesium binding site 2 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1902 b:20.0 occ:1.00 OP2 z:A342 2.9 0.0 1.0 P z:A342 4.0 0.0 1.0 OP1 z:A342 4.1 0.0 1.0 O6 1:G1837 4.4 20.0 1.0 O5' z:A342 4.8 0.0 1.0 N2 1:G1836 4.9 20.0 1.0

Magnesium binding site 3 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1903 b:20.0 occ:1.00 O4 1:U1830 3.9 20.0 1.0 OP2 1:C1828 4.1 20.0 1.0 N7 1:G1829 4.6 20.0 1.0 C5 1:C1828 4.7 20.0 1.0 C4 1:U1830 5.0 20.0 1.0

Magnesium binding site 4 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1904 b:20.0 occ:1.00 OP2 1:G598 3.2 20.0 1.0 OP1 1:G598 3.7 20.0 1.0 P 1:G598 3.7 20.0 1.0 O5' 1:G598 4.1 20.0 1.0 OP1 1:C633 4.2 20.0 1.0 OP2 1:A599 4.5 20.0 1.0 OP2 1:C633 4.9 20.0 1.0 OP1 1:A619 4.9 20.0 1.0

Magnesium binding site 5 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1905 b:20.0 occ:1.00 OP2 1:C632 4.1 20.0 1.0 OP2 1:C633 4.7 20.0 1.0 N6 1:A599 4.9 20.0 1.0 O6 1:G606 5.0 20.0 1.0

Magnesium binding site 6 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1906 b:20.0 occ:1.00 OP1 1:U1243 3.3 20.0 1.0 O6 1:G1520 4.5 20.0 1.0 O2' 1:U1242 4.6 20.0 1.0 P 1:U1243 4.6 20.0 1.0 O3' 1:C1518 4.8 20.0 1.0 OP2 1:C1234 4.9 20.0 1.0 OP2 1:U1519 5.0 20.0 1.0

Magnesium binding site 7 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1907 b:20.0 occ:1.00 O2' 1:G1089 2.9 20.0 1.0 OP2 1:U675 4.0 20.0 1.0 C2' 1:G1089 4.0 20.0 1.0 C1' 1:G1089 4.0 20.0 1.0 OP1 1:C1026 4.4 20.0 1.0 OP1 1:C674 4.5 20.0 1.0 N7 1:A672 4.6 20.0 1.0 O4' 1:G1089 4.6 20.0 1.0 MG 1:MG1927 4.7 20.0 1.0 OP2 1:C674 4.9 20.0 1.0 C8 1:A672 5.0 20.0 1.0

Magnesium binding site 8 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1908 b:20.0 occ:1.00 O a:GLY16 3.9 20.0 1.0 OP2 1:A1084 4.2 20.0 1.0 OP2 1:G999 4.3 20.0 1.0 OP1 1:A998 4.3 20.0 1.0 O3' 1:G1858 4.4 20.0 1.0 OP1 1:G999 4.6 20.0 1.0 OP1 1:A1859 4.6 20.0 1.0 C a:GLY16 4.6 20.0 1.0 P 1:G999 4.7 20.0 1.0 O2' 1:G1858 4.7 20.0 1.0 O3' 1:A998 4.8 20.0 1.0 C5' 1:A998 4.8 20.0 1.0 CA a:GLY16 4.9 20.0 1.0 N1 1:A1082 4.9 20.0 1.0

Magnesium binding site 9 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1909 b:20.0 occ:1.00 N7 1:G1104 3.5 20.0 1.0 C8 1:G1104 4.2 20.0 1.0 C5 1:G1104 4.4 20.0 1.0 N7 1:G1105 4.5 20.0 1.0 O6 1:G1104 4.5 20.0 1.0 O6 1:G1105 4.5 20.0 1.0 N4 1:C1103 4.8 20.0 1.0 C6 1:G1104 4.8 20.0 1.0

Magnesium binding site 10 out of 74 in the Mammalian 40S Hcv-Ires Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of Mammalian 40S Hcv-Ires Complex within 5.0Å range: probe atom residue distance (Å) B Occ 1:Mg1910 b:20.0 occ:1.00 O2' 1:C1527 3.7 20.0 1.0 OP1 1:C1254 4.0 20.0 1.0 NZ U:LYS75 4.2 20.0 1.0 CE U:LYS75 4.3 20.0 1.0 OP1 1:A1253 4.6 20.0 1.0 C4' 1:C1527 4.6 20.0 1.0 CB Q:TYR141 4.7 20.0 1.0 C2' 1:C1527 4.9 20.0 1.0 O3' 1:C1527 4.9 20.0 1.0 CG Q:TYR141 5.0 20.0 1.0 O4' 1:C1527 5.0 20.0 1.0

H.Yamamoto, M.Collier, J.Loerke, J.Ismer, A.Schmidt, T.Hilal, T.Sprink, K.Yamamoto, T.Mielke, J.Burger, T.R.Shaikh, M.Dabrowski, P.W.Hildebrand, P.Scheerer, C.M.Spahn. Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site Rna. Embo J. V. 34 3042 2015.
ISSN: ISSN 0261-4189
PubMed: 26604301
DOI: 10.15252/EMBJ.201592469