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Atomistry » Magnesium » PDB 4nm0-4nxn » 4nmm » |
Magnesium in PDB 4nmm: Crystal Structure of A G12C Oncogenic Variant of Human Kras Bound to A Novel Gdp Competitive Covalent InhibitorEnzymatic activity of Crystal Structure of A G12C Oncogenic Variant of Human Kras Bound to A Novel Gdp Competitive Covalent Inhibitor
All present enzymatic activity of Crystal Structure of A G12C Oncogenic Variant of Human Kras Bound to A Novel Gdp Competitive Covalent Inhibitor:
3.6.5.2; Protein crystallography data
The structure of Crystal Structure of A G12C Oncogenic Variant of Human Kras Bound to A Novel Gdp Competitive Covalent Inhibitor, PDB code: 4nmm
was solved by
J.C.Hunter,
D.Gurbani,
S.M.Lim,
K.D.Westover,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of A G12C Oncogenic Variant of Human Kras Bound to A Novel Gdp Competitive Covalent Inhibitor
(pdb code 4nmm). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of A G12C Oncogenic Variant of Human Kras Bound to A Novel Gdp Competitive Covalent Inhibitor, PDB code: 4nmm: Magnesium binding site 1 out of 1 in 4nmmGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of A G12C Oncogenic Variant of Human Kras Bound to A Novel Gdp Competitive Covalent Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.C.Hunter,
D.Gurbani,
S.B.Ficarro,
M.A.Carrasco,
S.M.Lim,
H.G.Choi,
T.Xie,
J.A.Marto,
Z.Chen,
N.S.Gray,
K.D.Westover.
In Situ Selectivity Profiling and Crystal Structure of Sml-8-73-1, An Active Site Inhibitor of Oncogenic K-Ras G12C. Proc.Natl.Acad.Sci.Usa V. 111 8895 2014.
Page generated: Mon Aug 19 23:43:31 2024
ISSN: ISSN 0027-8424 PubMed: 24889603 DOI: 10.1073/PNAS.1404639111 |
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