Magnesium in PDB 6pl8: Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp

All present enzymatic activity of Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp:
2.7.7.7;

The structure of Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp, PDB code: 6pl8 was solved by M.C.Koag, S.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.87 / 2.17
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	98.705, 98.705, 81.719, 90.00, 90.00, 120.00
R / Rfree (%)	18.2 / 24.4

The binding sites of Magnesium atom in the Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp (pdb code 6pl8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp, PDB code: 6pl8:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:22.5 occ:1.00 OD2 A:ASP13 2.0 21.5 1.0 O1A A:1FZ501 2.0 27.4 1.0 O2G A:1FZ501 2.1 20.0 1.0 O2B A:1FZ501 2.2 20.9 1.0 O A:MET14 2.2 21.7 1.0 OD2 A:ASP115 2.2 20.1 1.0 CG A:ASP13 3.0 21.7 1.0 PB A:1FZ501 3.2 24.6 1.0 PA A:1FZ501 3.2 28.6 1.0 CG A:ASP115 3.2 25.8 1.0 C A:MET14 3.4 20.0 1.0 MG A:MG503 3.4 21.4 1.0 OD1 A:ASP13 3.4 23.9 1.0 PG A:1FZ501 3.5 24.6 1.0 N3A A:1FZ501 3.6 27.3 1.0 OD1 A:ASP115 3.7 26.9 1.0 O3B A:1FZ501 3.7 24.8 1.0 N A:MET14 3.9 17.6 1.0 NZ A:LYS231 3.9 19.1 1.0 O1G A:1FZ501 4.0 21.2 1.0 O5' A:1FZ501 4.1 25.9 1.0 CA A:MET14 4.1 19.7 1.0 C5' A:1FZ501 4.1 28.4 1.0 C A:ASP13 4.2 19.9 1.0 CB A:ASP13 4.2 20.7 1.0 O A:HOH635 4.3 21.0 1.0 N A:ASP15 4.4 17.8 1.0 CB A:ASP115 4.5 14.9 1.0 O2A A:1FZ501 4.5 24.1 1.0 N A:CYS16 4.5 18.1 1.0 CA A:ASP15 4.6 21.7 1.0 O A:ASP13 4.6 17.3 1.0 O3G A:1FZ501 4.6 25.2 1.0 CA A:ASP13 4.7 20.1 1.0 O1B A:1FZ501 4.7 25.1 1.0 CB A:MET14 4.7 19.8 1.0 CE A:LYS231 4.7 23.6 1.0 C A:ASP15 4.7 20.5 1.0 N A:PHE17 4.8 15.8 1.0 O A:ASP115 4.9 23.0 1.0 CB A:PHE17 4.9 15.2 1.0

Magnesium binding site 2 out of 2 in the Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg503 b:21.4 occ:1.00 OE1 A:GLU116 1.9 21.3 1.0 O A:HOH635 2.0 21.0 1.0 OD1 A:ASP13 2.1 23.9 1.0 O1A A:1FZ501 2.2 27.4 1.0 OD1 A:ASP115 2.2 26.9 1.0 O3' P:DT8 2.4 28.0 1.0 CD A:GLU116 3.0 23.5 1.0 CG A:ASP13 3.1 21.7 1.0 PA A:1FZ501 3.1 28.6 1.0 CG A:ASP115 3.1 25.8 1.0 C3' P:DT8 3.3 26.5 1.0 OD2 A:ASP115 3.3 20.1 1.0 MG A:MG502 3.4 22.5 1.0 OD2 A:ASP13 3.4 21.5 1.0 O2A A:1FZ501 3.5 24.1 1.0 O5' A:1FZ501 3.7 25.9 1.0 OE2 A:GLU116 3.7 24.4 1.0 OG A:SER113 3.9 19.2 1.0 CG A:GLU116 4.1 19.9 1.0 C5' A:1FZ501 4.2 28.4 1.0 CB A:GLU116 4.2 21.3 1.0 C4' P:DT8 4.2 25.8 1.0 NZ A:LYS224 4.3 28.8 1.0 CB A:ASP13 4.4 20.7 1.0 C2' P:DT8 4.5 23.6 1.0 CB A:ASP115 4.5 14.9 1.0 O2G A:1FZ501 4.6 20.0 1.0 C A:ASP115 4.6 22.4 1.0 N3A A:1FZ501 4.7 27.3 1.0 O A:ASP115 4.7 23.0 1.0 O2B A:1FZ501 4.8 20.9 1.0 N A:GLU116 4.8 21.0 1.0 C5' P:DT8 4.9 29.9 1.0

M.C.Koag, S.Lee. Structure of Human Dna Polymerase Eta Complexed with 8OA in the Template Base Paired with Incoming Non-Hydrolyzable Ttp To Be Published.