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Magnesium in PDB 7txh: Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA
Enzymatic activity of Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA
All present enzymatic activity of Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA:
3.1.3.16; 3.6.5.2;
3.1.3.16; 3.6.5.2;
Protein crystallography data
The structure of Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA, PDB code: 7txh
was solved by
Z.J.Hauseman,
J.Viscomi,
A.Dhembi,
K.Clark,
D.A.King,
M.Fodor,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 42.26 / 1.95 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 72.959, 115.755, 137.804, 90, 100.31, 90 |
| R / Rfree (%) | 16.7 / 21 |
Other elements in 7txh:
The structure of Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA also contains other interesting chemical elements:
| Manganese | (Mn) | 4 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA
(pdb code 7txh). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA, PDB code: 7txh:
Jump to Magnesium binding site number: 1; 2;
In total 2 binding sites of Magnesium where determined in the Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA, PDB code: 7txh:
Jump to Magnesium binding site number: 1; 2;
Magnesium binding site 1 out of 2 in 7txh
Go back to
Magnesium Binding Sites List in 7txh
Magnesium binding site 1 out
of 2 in the Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA within 5.0Å range:
|
Magnesium binding site 2 out of 2 in 7txh
Go back to
Magnesium Binding Sites List in 7txh
Magnesium binding site 2 out
of 2 in the Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Human Mras Q71R in Complex with Human SHOC2 Lrr Domain M173I and Human PP1CA within 5.0Å range:
|
Reference:
Z.J.Hauseman,
M.Fodor,
A.Dhembi,
J.Viscomi,
D.Egli,
M.Bleu,
S.Katz,
E.Park,
D.M.Jang,
K.A.Porter,
F.Meili,
H.Guo,
G.Kerr,
S.Molle,
C.Velez-Vega,
K.S.Beyer,
G.G.Galli,
S.M.Maira,
T.Stams,
K.Clark,
M.J.Eck,
L.Tordella,
C.R.Thoma,
D.A.King.
Structure of the Mras-SHOC2-PP1C Phosphatase Complex. Nature V. 609 416 2022.
ISSN: ESSN 1476-4687
PubMed: 35830882
DOI: 10.1038/S41586-022-05086-1
Page generated: Thu Oct 3 09:34:15 2024
ISSN: ESSN 1476-4687
PubMed: 35830882
DOI: 10.1038/S41586-022-05086-1
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