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Atomistry » Magnesium » PDB 8k7c-8of0 » 8oeg | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 8k7c-8of0 » 8oeg » |
Magnesium in PDB 8oeg: PDE4B Bound to Mapi Compound 92AEnzymatic activity of PDE4B Bound to Mapi Compound 92A
All present enzymatic activity of PDE4B Bound to Mapi Compound 92A:
3.1.4.53; Protein crystallography data
The structure of PDE4B Bound to Mapi Compound 92A, PDB code: 8oeg
was solved by
A.Rizzi,
E.Armani,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8oeg:
The structure of PDE4B Bound to Mapi Compound 92A also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the PDE4B Bound to Mapi Compound 92A
(pdb code 8oeg). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the PDE4B Bound to Mapi Compound 92A, PDB code: 8oeg: Magnesium binding site 1 out of 1 in 8oegGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the PDE4B Bound to Mapi Compound 92A
![]() Mono view ![]() Stereo pair view
Reference:
E.Armani,
A.Rizzi,
C.Capaldi,
R.De Fanti,
M.Delcanale,
G.Villetti,
G.Marchini,
A.R.Pisano,
V.Pitozzi,
M.G.Pittelli,
M.Trevisani,
M.Salvadori,
V.Cenacchi,
P.Puccini,
F.Amadei,
A.Pappani,
M.Civelli,
R.Patacchini,
C.A.G.Baker-Glenn,
H.Van De Poel,
W.P.Blackaby,
K.Nash,
G.Amari.
Discovery of M 3 Antagonist-PDE4 Inhibitor Dual Pharmacology Molecules For the Treatment of Chronic Obstructive Pulmonary Disease. J.Med.Chem. V. 64 9100 2021.
Page generated: Fri Oct 4 14:41:35 2024
ISSN: ISSN 0022-2623 PubMed: 34142835 DOI: 10.1021/ACS.JMEDCHEM.1C00204 |
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