Magnesium in PDB 8q8p: Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State

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>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 24;

Binding sites:

The binding sites of Magnesium atom in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State (pdb code 8q8p). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 24 binding sites of Magnesium where determined in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State, PDB code: 8q8p:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Magnesium binding site 1 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg601 b:21.8 occ:1.00 OE2 A:GLU374 2.9 46.5 1.0 OE2 A:GLU378 2.9 40.5 1.0 CD A:GLU374 3.4 42.8 1.0 OE1 A:GLU374 3.7 46.5 1.0 CD A:GLU378 4.0 41.2 1.0 OD2 B:ASP350 4.2 54.1 1.0 CG A:GLU374 4.3 40.9 1.0 OE1 A:GLU378 4.4 41.5 1.0 OD1 B:ASP350 4.4 51.9 1.0 OD2 B:ASP349 4.5 57.7 1.0 CG B:ASP350 4.7 53.5 1.0

Magnesium binding site 2 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:46.2 occ:1.00 NE2 A:HIS370 2.7 52.9 1.0 CD2 A:HIS370 3.4 52.0 1.0 OE2 A:GLU374 3.6 46.5 1.0 OE1 A:GLU374 3.7 46.5 1.0 CE1 A:HIS370 3.8 53.5 1.0 CD A:GLU374 3.9 42.8 1.0 CG A:HIS370 4.7 52.7 1.0 ND1 A:HIS370 4.8 52.0 1.0 OD1 A:ASP348 4.9 54.5 1.0

Magnesium binding site 3 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg603 b:39.5 occ:1.00 OE1 B:GLN332 3.0 40.4 1.0 OG A:SER396 3.3 35.0 1.0 CD B:GLN332 3.5 31.5 1.0 OD1 A:ASN393 3.5 34.4 1.0 CB B:GLN332 3.7 21.9 1.0 O B:SER328 3.8 36.9 1.0 CA A:ASN393 4.0 18.7 1.0 CB A:SER396 4.0 33.1 1.0 CG B:GLN332 4.1 28.4 1.0 C B:SER328 4.2 28.7 1.0 NE2 B:GLN332 4.2 23.4 1.0 CG A:ASN393 4.3 33.1 1.0 CB A:ASN393 4.3 23.3 1.0 CA B:THR329 4.4 22.8 1.0 OG B:SER328 4.5 37.0 1.0 N B:THR329 4.5 17.9 1.0 CB B:SER328 4.5 23.8 1.0 MG B:MG601 4.7 32.7 1.0 N A:ASN393 4.7 22.7 1.0 O A:ASN393 4.8 30.7 1.0 O A:SER392 4.9 34.4 1.0 OG1 B:THR329 4.9 30.3 1.0 C A:ASN393 5.0 24.2 1.0 CA B:SER328 5.0 23.4 1.0

Magnesium binding site 4 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg604 b:32.7 occ:1.00 OG A:SER328 2.6 37.0 1.0 O A:LYS325 3.2 45.6 1.0 OG E:SER397 3.3 42.3 1.0 CB A:LYS325 3.3 39.7 1.0 CA A:LYS325 3.3 37.0 1.0 OG E:SER396 3.6 35.0 1.0 OG1 A:THR329 3.6 30.3 1.0 C A:LYS325 3.7 38.3 1.0 ND2 E:ASN400 3.9 47.0 1.0 CB A:SER328 3.9 23.8 1.0 N E:SER397 3.9 35.8 1.0 CA E:SER397 4.0 30.6 1.0 CB E:SER397 4.2 33.1 1.0 C E:SER396 4.3 33.3 1.0 CB E:SER396 4.4 33.1 1.0 OD1 E:ASN393 4.4 34.4 1.0 O E:ASN393 4.4 30.7 1.0 N A:THR329 4.4 17.9 1.0 O E:SER396 4.6 32.7 1.0 MG A:MG605 4.7 39.5 1.0 N A:LYS325 4.7 35.0 1.0 CG A:LYS325 4.8 37.4 1.0 CB A:THR329 4.9 24.6 1.0 C A:SER328 4.9 28.7 1.0 CA A:SER328 4.9 23.4 1.0 CG E:ASN393 5.0 33.1 1.0 N A:ARG326 5.0 26.1 1.0

Magnesium binding site 5 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg605 b:39.5 occ:1.00 OE1 A:GLN332 3.0 40.4 1.0 OG E:SER396 3.3 35.0 1.0 CD A:GLN332 3.5 31.5 1.0 OD1 E:ASN393 3.5 34.4 1.0 CB A:GLN332 3.7 21.9 1.0 O A:SER328 3.8 36.9 1.0 CA E:ASN393 4.0 18.7 1.0 CB E:SER396 4.0 33.1 1.0 CG A:GLN332 4.1 28.4 1.0 C A:SER328 4.2 28.7 1.0 NE2 A:GLN332 4.2 23.4 1.0 CG E:ASN393 4.3 33.1 1.0 CB E:ASN393 4.3 23.3 1.0 CA A:THR329 4.4 22.8 1.0 N A:THR329 4.4 17.9 1.0 OG A:SER328 4.5 37.0 1.0 CB A:SER328 4.5 23.8 1.0 MG A:MG604 4.7 32.7 1.0 N E:ASN393 4.7 22.7 1.0 O E:ASN393 4.8 30.7 1.0 O E:SER392 4.8 34.4 1.0 OG1 A:THR329 4.9 30.3 1.0 C E:ASN393 4.9 24.2 1.0 CA A:SER328 5.0 23.4 1.0

Magnesium binding site 6 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg606 b:67.8 occ:1.00 OD1 E:ASN443 4.6 18.6 1.0 OD1 D:ASN443 4.6 18.6 1.0 OD1 A:ASN443 4.6 18.6 1.0 OD1 C:ASN443 4.6 18.6 1.0 OD1 B:ASN443 4.6 18.6 1.0 MG A:MG607 4.7 74.5 1.0

Magnesium binding site 7 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg607 b:74.5 occ:1.00 O E:GLY441 4.1 15.9 1.0 O D:GLY441 4.1 15.9 1.0 O C:GLY441 4.1 15.9 1.0 O A:GLY441 4.2 15.9 1.0 O B:GLY441 4.2 15.9 1.0 OD1 D:ASN443 4.5 18.6 1.0 OD1 E:ASN443 4.5 18.6 1.0 OD1 C:ASN443 4.5 18.6 1.0 OD1 A:ASN443 4.5 18.6 1.0 OD1 B:ASN443 4.5 18.6 1.0 MG A:MG606 4.7 67.8 1.0

Magnesium binding site 8 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg608 b:90.6 occ:1.00 CG2 C:THR434 4.6 18.8 1.0 CG2 E:THR434 4.6 18.8 1.0 CG2 B:THR434 4.6 18.8 1.0 CG2 A:THR434 4.6 18.8 1.0 CG2 D:THR434 4.6 18.8 1.0

Magnesium binding site 9 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 9 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg601 b:32.7 occ:1.00 OG B:SER328 2.6 37.0 1.0 O B:LYS325 3.2 45.6 1.0 OG A:SER397 3.3 42.3 1.0 CB B:LYS325 3.3 39.7 1.0 CA B:LYS325 3.3 37.0 1.0 OG A:SER396 3.6 35.0 1.0 OG1 B:THR329 3.6 30.3 1.0 C B:LYS325 3.7 38.3 1.0 ND2 A:ASN400 3.9 47.0 1.0 CB B:SER328 3.9 23.8 1.0 N A:SER397 3.9 35.8 1.0 CA A:SER397 4.0 30.6 1.0 CB A:SER397 4.2 33.1 1.0 C A:SER396 4.3 33.3 1.0 CB A:SER396 4.4 33.1 1.0 OD1 A:ASN393 4.4 34.4 1.0 O A:ASN393 4.4 30.7 1.0 N B:THR329 4.5 17.9 1.0 O A:SER396 4.6 32.7 1.0 MG A:MG603 4.7 39.5 1.0 N B:LYS325 4.7 35.0 1.0 CG B:LYS325 4.8 37.4 1.0 CB B:THR329 4.9 24.6 1.0 C B:SER328 4.9 28.7 1.0 CA B:SER328 4.9 23.4 1.0 CG A:ASN393 5.0 33.1 1.0 N B:ARG326 5.0 26.1 1.0

Magnesium binding site 10 out of 24 in the Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 10 of Cryo-Em Strcuture of the Magnesium Channel CTMRS2 in the Closed State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg602 b:21.8 occ:1.00 OE2 B:GLU374 2.9 46.5 1.0 OE2 B:GLU378 2.9 40.5 1.0 CD B:GLU374 3.4 42.8 1.0 OE1 B:GLU374 3.7 46.5 1.0 CD B:GLU378 4.0 41.2 1.0 OD2 C:ASP350 4.1 54.1 1.0 CG B:GLU374 4.3 40.9 1.0 OE1 B:GLU378 4.4 41.5 1.0 OD1 C:ASP350 4.4 51.9 1.0 OD2 C:ASP349 4.5 57.7 1.0 CG C:ASP350 4.7 53.5 1.0

P.E.Gourdon, P.Li. Cryo-Em Strcutural Insight Into the Magnesium Channel CTMRS2 To Be Published.
DOI: 10.1038/S41594-024-01432-1